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ProteomicsPRM quantification of MCS proteins and viral proteins in HCMV virus microenvironment
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. We establis...
ORGANISM(S): Homo Sapiens Human Betaherpesvirus 5 
PXD038466 | panorama
UnknownTiming Selector: Using Transient Switching Dynamics to Solve the Sneak Path Issue of Crossbar Arrays.
Not available
S-EPMC11936054 | biostudies-literature
TranscriptomicsA functional genomics predictive network model identifies regulators of inflammatory bowel disease: Microarray Analysis of Human Blood and Intestinal Biopsy Samples from a Phase 2b, Double-blind, Placebo-controlled Study of Ustekinumab in Crohn's Disease
Microarray Analysis of Human Whole Blood and Intestinal Biopsy Samples from a Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Ustekinumab in Crohn’s Disease 329 Crohn's biopsies from multiple regions in the intestine of 87 anti TNFa refractory patients an...
ORGANISM(S): Homo sapiens 
2017-07-07 | E-GEOD-100833 | biostudies-arrayexpress
ProteomicsOxidative stress induces lysosomal membrane permeabilization and ceramide accumulation in retinal pigment epithelial cells
Oxidative stress has been implicated in the pathogenesis of age-related macular degeneration(AMD), the leading cause of blindness in the elderly, with retinal pigment epithelial (RPE) cells playing a key role. To better understand the cytotoxic mechanisms underlying oxidative stress, we used cell cu...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-19 | PXD043613 | Pride
Oxidative stress Lysosome Age-related macular degeneration Aging Retina 
TranscriptomicsGene Expression Profiles in Early Stages Uterine Serous Carcinomas in comparison to G3 and G1 Endometrioid Adenocarcinoma
The goal of this study was to identify differentially expressed genes (DEG) between uterine serouscarcinoma (USC) vs. early stages high/low grade endometrioid adenocarcinoma (EAC). Gene expression profiles of 33 cancer samples were analyzed (EAC-G1=11, EAC-G3=11, USC-G3=11) using the human genome wi...
ORGANISM(S): Homo sapiens 
2011-03-31 | E-GEOD-24537 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis Reveals Distinct Gene Expression Profiles Among Different Tumor Histology, Stage and Disease Outcomes in Endometrial Adenocarcinoma
The goal of this study was to identify differentially expressed genes (DEG) between early vs. late stage endometrioid adenocarcinoma (EAC) and uterine serous carcinoma (USC), as well as between disease outcomes in each of the two histological subtypes. Gene expression profiles of 20 cancer samples w...
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-23518 | biostudies-arrayexpress
ProteomicsHigh-throughput and high-efficiency sample preparation for single-cell proteomics using a nested nanowell chip
Development and evaluation of nested nanowell (N2) chip in single-cell proteomics. The newly designed chip helps to improve the sensitivity and robustness of the tandem mass tag labeling approach by sizing down wells.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-02-04 | MSV000086809 | MassIVE
ProteomicsProteomics of the developing human lung
Proteomic data from human lung collected from human donors spanning 10 timepoints between 1 day old and 8 years old. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-08-07 | MSV000085929 | MassIVE
ProteomicsProteogenomic analysis of chemo-refractory high grade serous ovarian cancer
To improve our understanding of the molecular basis of chemo-refractory high grade serous ovarian cancers (HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) HGSOCs, representing one discovery and two independent validation cohorts (spanning four academic centers...
ORGANISM(S): Homo Sapiens 
PXD040742 | panorama
UnknownGlobal, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990-2021: findings from the Global Burden of Disease Study 2021.
Not available
S-EPMC11694012 | biostudies-literature
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