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MetabolomicsAbsence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in Aeromonas veronii
Bacterial persisters are a small proportion of phenotypically heterogeneous variants with the transient capability to survive in high concentrations of antibiotics, causing recurrent infections in both human and aquatic animals. Transfer-messenger RNA (tmRNA), which was encoded by the ssrA ge...
2021-10-18 | MTBLS1182 | MetaboLights
UnknownDiscovery of Isoindoline Amide Derivatives as Potent and Orally Bioavailable ADAMTS-4/5 Inhibitors for the Treatment of Osteoarthritis.
Not available
S-EPMC9274773 | biostudies-literature
UnknownSHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Not available
S-EPMC9122897 | biostudies-literature
ProteomicsIdentification of BRCA2-DSS1 new partner HELZ
R-loops are dynamic three-stranded nucleic acid structures that regulate genome function but can threaten genome stability if not properly resolved. BRCA2, a key player in homologous recombination (HR), also regulates R-loops, though the mechanisms remain unclear. To uncover novel R-loop regulators,...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD066766 | Pride
Hela Biotinid-dss1 Brca2 Helz 
ProteomicsProteomics analysis of guinea pig skin in melanin deposition model
Differential expression of proteinomic changes and key signaling pathways in the skin of guinea pigs that were subjected to two distinct modeling methods that led to melanin deposition. These two modelling methods are pure ultraviolet radiation method and combined ultraviolet radiation method with p...
ORGANISM(S): Cavia Porcellus 
2023-07-12 | PXD043697 |
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
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