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TranscriptomicsHuman Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
We generated induced human hepatocyte by transduction of several lineage specific transcription factors and analyzed the gene expression profile of generated hepatocytes and freshly isolated human hepatocytes through RNA sequencing. Global gene expression profile analysis
ORGANISM(S): Homo sapiens 
2014-03-10 | E-GEOD-54066 | biostudies-arrayexpress
ProteomicsN Gene TurboID (Group2 +p50)
Nicotiana benthamiana plants were infiltrated with three different constructs: 1) N-TurboID-3HA 2) NTIR-TurboID-3HA or 3) Citrine-TurboID-3HA. N-TurboID is the full length N-gene fused to TurboID, NTIR-Turbo is the TIR domain of the N-gene fused to turboID, and Citrine-TurboID is the control constru...
ORGANISM(S): Nicotiana Benthamiana (ncbitaxon:4100) 
2018-10-10 | MSV000083019 | MassIVE
ProteomicsN Gene TurboID (Group1 -p50)
Nicotiana benthamiana plants were infiltrated with three different constructs: 1) N-TurboID-3HA 2) NTIR-TurboID-3HA or 3) Citrine-TurboID-3HA. N-TurboID is the full length N-gene fused to TurboID, NTIR-Turbo is the TIR domain of the N-gene fused to turboID, and Citrine-TurboID is the control constru...
ORGANISM(S): Nicotiana Benthamiana (ncbitaxon:4100) 
2018-10-10 | MSV000083018 | MassIVE
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicsCCL20/CXCL5 regulates the stemness of anaplastic thyroid cancer stem cells via NF-kB pathway
The mechanism of CCL20/CXCL5 regulating anaplastic thyroid cancer cancer stem cells to promote the progression of thyroid cancer
ORGANISM(S): Homo Sapiens 
2023-11-13 | PXD046889 |
ProteomicsCo-IP and LC-MS/MS analysis for probing the binding partners of ITGBL1 in fibroblasts
Co-IP, LC-MS/MS and cluster analysis of the binding proteins for targeted ITGBL1 protein using the ITGBL1 antibody or control IgG in ITGBL1-overexpressing WI-38 cells.
ORGANISM(S): Homo Sapiens 
2020-01-19 | PXD017182 |
ProteomicsTandem proteomic and N-glycoproteomic analysis of extracellular vesicles
Extracellular vesicles (EVs) derived from diverse biofluids have emerged as promising noninvasive diagnostic biomarkers or signatures for various diseases. EV-associated N-glycoproteins are crucial for the biological functions of EVs and hold significant potential for disease diagnosis and prognosis...
ORGANISM(S): Homo Sapiens 
2024-11-05 | PXD057512 |
Proteomicsproteomic and N-glycoproteomic analysis of extracellular vesicles for biofluids
Extracellular vesicles (EVs) derived from diverse biofluids have emerged as promising noninvasive diagnostic biomarkers or signatures for various diseases. EV-associated N-glycoproteins are crucial for the biological functions of EVs and hold significant potential for disease diagnosis and prognosis...
ORGANISM(S): Homo Sapiens 
2024-11-05 | PXD057515 |
ProteomicsProteogenomic landscape of the Esophageal Squamous Cell Cancer reveals the lipid droplet formation process as a novel therapeutic target
The integrated proteogenomic analysis revealed proteomic characteristics associated with genomic variants and clinical features including arm or focal amplifications, SNV mutations, tumor size, lymph node metastasis, smoking history.
ORGANISM(S): Homo Sapiens 
2025-03-24 | PXD062163 |
ProteomicsFecal protein changes in different colorectal diseases
We examined fecal proteins from normal subjects (n=6), patients with inflammatory bowel disease (n=8), patients with colorectal adenoma (n=8), and patients with colorectal cancer (n=14) in the hope of identifying novel fecal protein markers that could be used to identify colorectal diseases.
ORGANISM(S): Homo Sapiens 
2022-12-22 | PXD039089 |
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