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Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. However, the mechanisms underlying Treg function and cell fate decisions to differentiate between Treg and conventional T cells (Tconv) remain to be fully elucidated, especially at t...
ORGANISM(S): Homo sapiens 
Protein quantification by iTRAQ was carried out according to the method of Lu et al. (2017). Equally mixed peptides were analyzed by Majorbio Biopharm Technology Co., Ltd. The mixed peptides were preseparated via a C18 reversed-phase column and analyzed via liquid chromatography coupled with tandem ...
ORGANISM(S): Taiwanofungus Camphoratus 
2020-03-11 | PXD018004 |
Stress granules are known to be related with selective translation. To determine which proteins are regulated by stress granules assembly in Ptenα─/─ MEFs, we performed a mass spectrometry analysis of Ptenα+/+ and Ptenα─/─ MEFs under oxidative stress.
ORGANISM(S): Mus Musculus 
2020-10-03 | PXD021840 |
PTENα is the first isoform of tumor suppressor PTEN. To investigate the molecular mechanism by which PTENα modulates cell response to inflammation, we performed pull-down assays with FLAG-tagged proteins coupled with mass spectrometry under condition of H2O2 treatment in B16 cells.
ORGANISM(S): Mus Musculus 
2021-07-13 | PXD040709 |
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