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Traditional genome annotation methods exclude Open Reading Frames shorter than 300 codons (smORFs), which leaves a substantial portion of the proteome overlooked. Proteogenomics is a multi-omics approach that merges genomics, transcriptomics and proteomics to identify proteoforms and unannotated pro...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2025-05-06 | PXD042958 | Pride
Methyl methanesulfonate (MMS) is a DNA damage agent that induces the DNA damage response (DDR). Recent findings in the literature suggest a role for phosphatidylinositol signaling in regulating the DDR. In budding yeast, inositol biosynthesis is fine-tuned by the transcriptional repressor Opi1. We c...
ORGANISM(S): Saccharomyces cerevisiae 
Uncovering the role of upstream ORFs (uORFs) challenges conventional views of one protein per mRNA while also revealing the capacity of some uORFs to encode microproteins that contribute to cellular biology and physiology. This study explores the functional role of a recently identified mitochondria...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-29 | PXD066679 | Pride

Grape juice is a major source of potential health-promoting bioactive polyphenols, especially for children and those who do not consume wine. Since the subtropical climate may negatively affect the concentrations of grape polyphenols, especially anthocyanins, elicitors such as methyl jasmonate (M...

2022-06-28 | MTBLS2401 | MetaboLights
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