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ProteomicsNeutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes
Streptococcus pyogenes (group A streptococci; GAS) is the main causative pathogen of monomicrobial necrotizing soft tissue infections (NSTIs). To resist immuno-clearance, GAS adapt their genetic information and/or phenotype to the surrounding environment. Hyper-virulent streptococcal pyrogenic exoto...
ORGANISM(S): Streptococcus pyogenes M1 GAS Homo sapiens (Human) Streptococcus pyogenes MGAS315 
2023-10-24 | PXD040160 | Pride
Speb Necrotizing soft tissue infections Neutrophils Streptococcus pyogenes 
TranscriptomicsGeneral retardation of mRNA degradation caused by speB 5’ UTR partial deletion in Streptococcus pyogenes
The speB gene of Streptococcus pyogenes has a long 5' UTR with unknown functions. Preliminary studies showed that the partial mutation of this region led to altered expression patterns of the speB gene and ropB, its upstream gene. In this study, we used microarray to examine the effect of speB 5' UT...
ORGANISM(S): Streptococcus pyogenes 
2015-09-10 | E-GEOD-72838 | biostudies-arrayexpress
TranscriptomicsGeneral retardation of mRNA degradation caused by speB 5’ UTR partial deletion in Streptococcus pyogenes
The speB gene of Streptococcus pyogenes has a long 5' UTR with unknown functions. Preliminary studies showed that the partial mutation of this region led to altered expression patterns of the speB gene and ropB, its upstream gene. In this study, we used microarray to examine the effect of speB 5' UT...
ORGANISM(S): Streptococcus pyogenes Streptococcus pyogenes NZ131 
2015-09-10 | GSE72838 | GEO
UnknownStructure of the E. coli agmatinase, SPEB.
Not available
S-EPMC8049259 | biostudies-literature
UnknownNeutrophil-derived reactive agents induce a transient SpeB negative phenotype in Streptococcus pyogenes.
Not available
S-EPMC10331992 | biostudies-literature
UnknownDifferences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease.
Not available
S-EPMC5435240 | biostudies-literature
UnknownInterference of a speB 5' untranslated region partial deletion with mRNA degradation in Streptococcus pyogenes.
Not available
S-EPMC10030001 | biostudies-literature
UnknownProteolytic Profiling of Streptococcal Pyrogenic Exotoxin B (SpeB) by Complementary HPLC-MS Approaches.
Not available
S-EPMC8745752 | biostudies-literature
UnknownRopB represses the transcription of speB in the absence of SIP in group A Streptococcus.
Not available
S-EPMC10071013 | biostudies-literature
UnknownRole of CsrR, hyaluronic acid, and SpeB in the internalization of Streptococcus pyogenes M type 3 strain by epithelial cells.
Not available
S-EPMC127687 | biostudies-literature
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