Sort   by:  
 Page size 
ProteomicsProteomic and Phosphoproteomic Analyses of Yeast Reveal the Global Cellular Response to Sphingolipid Depletion
Sphingolipids are essential components of eukaryotic cells with important functions in membrane biology and cellular signaling. Their levels are tightly controlled and coordinated with the abundance of other membrane lipids. How sphingolipid homeostasis is achieved is not yet well understood. Studie...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-12-23 | PXD003854 | Pride
Sphingolipid depletion Qexactive hf Phosphoproteomics Yeast 
UnknownArt2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion.
Not available
S-EPMC10399987 | biostudies-literature
UnknownProteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion.
Not available
S-EPMC5688516 | biostudies-literature
UnknownGOLM1 depletion modifies cellular sphingolipid metabolism and adversely affects cell growth.
Not available
S-EPMC9475319 | biostudies-literature
UnknownSphingolipid depletion suppresses UPR activation and promotes galactose hypersensitivity in yeast models of classic galactosemia.
Not available
S-EPMC9326788 | biostudies-literature
UnknownExtensive sphingolipid depletion does not affect lipid raft integrity or lipid raft localization and efflux function of the ABC transporter MRP1.
Not available
S-EPMC3791605 | biostudies-literature
UnknownAcid Ceramidase Depletion Impairs Neuronal Survival and Induces Morphological Defects in Neurites Associated with Altered Gene Transcription and Sphingolipid Content.
Not available
S-EPMC7084529 | biostudies-literature
ProteomicsMechanism of ORMDL proteins turnover via proteasome and autophagy is cell-type dependent and tied to ceramide homeostasis
ORMDL proteins are essential negative regulators of the serine palmitoyltransferase (SPT) complex, thereby controlling the rate of de novo sphingolipid synthesis. Although mammalian ORMDL proteins undergo rapid turnover, the mechanisms regulating their stability are not completely understood, with c...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD067431 | Pride
Autophagy Sphingolipid Lc3 Fumonisin b1 Proteasome degradation Ormdl3 Myriocin 
UnknownCholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis.
Not available
S-EPMC10547602 | biostudies-literature
TranscriptomicsmRNA expression data from keratinocytes with disorganized lipid raft structures (by cholesterol depletion by methyl-beta-cyclodextrin)
Lipid rafts are cholesterol-rich cell signaling platforms and their physiological role can be explored by cholesterol depletion. To dress a global picture of transcriptional changes ongoing after lipid raft disruption, we performed whole-genome expression profiling in epidermal keratinocytes, a cell...
ORGANISM(S): Homo sapiens 
2010-04-17 | E-GEOD-21364 | biostudies-arrayexpress
Sort   by:  
 Page size