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ProteomicsFAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning
The concerted action of many protein kinases helps orchestrate the error-free progression through mitosis of mammalian cells. The roles and regulation of some prominent mitotic kinases, such as cyclin-dependent kinases, are well-established. However, these and other known mitotic kinases alone canno...
ORGANISM(S): Homo sapiens (Human) 
2019-07-15 | PXD013808 | Pride
Protein kinase ck1α Mitotic spindle Fam83d 
ProteomicsMultisite phosphorylation of NuMA-related LIN-5 controls mitotic spindle positioning in C. elegans
Chromosome segregation and cleavage plane determination involves the generation of pulling forces on microtubules that extend from the centrosomes to the cell cortex. These forces depend on cortical anchoring of the cytoplasmic dynein motor by a conserved ternary complex of Galpha, GPR-1/2, and LIN-...
ORGANISM(S): Caenorhabditis elegans 
2018-10-26 | PXD004906 | Pride
Lin5 Spindle Phosphorylation 
UnknownChromosome misalignments induce spindle-positioning defects.
Not available
S-EPMC4772978 | biostudies-literature
UnknownMicrotubule organizing centers regulate spindle positioning in mouse oocytes.
Not available
S-EPMC8792338 | biostudies-literature
UnknownFAM83D directs protein kinase CK1α to the mitotic spindle for proper spindle positioning.
Not available
S-EPMC6726907 | biostudies-literature
UnknownCortical dynein is critical for proper spindle positioning in human cells.
Not available
S-EPMC3461507 | biostudies-literature
UnknownOptogenetic dissection of mitotic spindle positioning in vivo.
Not available
S-EPMC6214656 | biostudies-literature
TranscriptomicsChromosome positioning and the clustering of functionally related loci in yeast is driven by chromosomal interactions
In recent years there has been considerable and growing interest in the 3-dimensional organization of genomes. In yeast this has included detailed FISH studies that show a surprising degree of spatial clustering of the tRNA genes, the localization of telomeres, centromere positioning, and global stu...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-18 | E-GEOD-33018 | biostudies-arrayexpress
UnknownPhysical Limits on the Precision of Mitotic Spindle Positioning by Microtubule Pushing forces: Mechanics of mitotic spindle positioning.
Not available
S-EPMC5698852 | biostudies-literature
UnknownMitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins.
Not available
S-EPMC2136752 | biostudies-literature
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