Splenocytes - OmicsDI

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Repository

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geo (212)
pride (30)
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Tissue

Spleen (12)
T cell (8)
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Blood cell (1)
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Disease

Acute myeloid leukemia (1)
Myeloproliferative disorder (1)
Septic peritonitis (1)
Glioblastoma multiforme (1)
Colorectal Neoplasms (1)
Acute lymphocytic leukemia (1)
Lymphoma (1)
Malaria (1)
Multiple myeloma (1)
Schistosomiasis (1)
Tularemia (1)
Type 1 diabetes mellitus (1)

Technology Type

Mass Spectrometry (30)
Shotgun proteomics (18)
Bottom-up proteomics (7)
Data-dependent acquisition (4)
Data-independent acquisition (4)
Affinity purification coupled with mass spectrometry proteomics (3)
Mass spectrometry (2)
Mass spectrometry assay (1)
All-ion fragmentation (1)

Instrument Platform

Illumina NovaSeq 6000 (13)
NextSeq 500 (6)
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NextSeq 2000 (4)
Illumina MiSeq (4)
Illumina NovaSeq X (3)
NextSeq 550 (2)
Illumina HiSeq 2500 (2)
Illumina HiSeq 2000 (2)
Q Exactive (2)
LTQ Orbitrap Velos (2)
BD FACSAria™ III (1)
PromethION (1)
BD FACS Aria Cell Sorter (1)
Agilent Bioanalyser (1)
Miltenyi MACS isolation (1)
GeneChip Instrument System (1)
Affymetrix mouse gene 1.0 ST arrays (1)
BD FACSAria III (1)
Model 450 Fluidics Station/Affymetrix GeneChip Scanner 3000 TG System (1)
BD ARIA II Cell Sorter (1)
Agilent 2100 Bioanalyzer (1)
GenePix Personal 4100A [Axon Instruments] (1)
Illumina Genome Analyzer IIx (1)
ScanArray Express HT [PerkinElmer] (1)
DNBSEQ-G400 (1)
LTQ Orbitrap Elite (1)
Orbitrap Exploris 480 (1)
Q-Exactive Orbitrap (1)
ZenoTOF 7600 (1)

Publication Date

2015 (44)
2013 (42)
2014 (36)
2012 (35)
2021 (32)
2026 (30)
2022 (29)
2024 (28)
2016 (28)
2011 (28)
2010 (28)
2023 (27)
2025 (25)
2019 (23)
2018 (18)
2008 (18)
2020 (16)
2007 (16)
2017 (14)
2009 (13)
2005 (4)
2004 (4)
2006 (3)

UNIPROT ID/AC

A1L0U3 (1)
A1L347 (1)
A2A5N2 (1)
A2A7Z6 (1)
A2A838 (1)
A2AEE7 (1)
A2AR56 (1)
A2BI31 (1)
A2CG35 (1)
A2RSV8 (1)
A2RTT4 (1)
A3KGQ6 (1)
A3KML3 (1)
A4FUS1 (1)
A5GZX3 (1)
A6H6H4 (1)
A6ZI44 (1)
A7VJA4 (1)
A7VMS6 (1)
A8IP69 (1)
B1AQ77 (1)
B1AQ78 (1)
B1AR69 (1)
B2MWM9 (1)
B2RPS1 (1)
B2RRN5 (1)
B2RRX1 (1)
B2RSH2 (1)
B2RSV4 (1)
B2RTM0 (1)

ENSEMBL ID

ENSMUSG00000027651 (1)
ENSMUSP00000141097 (1)

CHEBI ID

CHEBI:27897 (2)
CHEBI:16335 (2)
CHEBI:16027 (2)
CHEBI:143024 (1)
CHEBI:173491 (1)
CHEBI:44514 (1)
CHEBI:24012 (1)
CHEBI:48537 (1)
CHEBI:140431 (1)
CHEBI:167505 (1)
CHEBI:17766 (1)
CHEBI:17500 (1)
CHEBI:27036 (1)
CHEBI:165524 (1)
CHEBI:507499 (1)
CHEBI:75144 (1)
CHEBI:18316 (1)
CHEBI:45296 (1)
CHEBI:140429 (1)
CHEBI:46968 (1)
CHEBI:16125 (1)
CHEBI:28286 (1)
CHEBI:79285 (1)
CHEBI:28458 (1)
CHEBI:64276 (1)
CHEBI:28082 (1)
CHEBI:16413 (1)
CHEBI:74112 (1)
CHEBI:26981 (1)
CHEBI:37684 (1)

Metabolite Name

Cholestane-3,5,6-triol, (3beta ,5alpha ,6beta)- (1)
Hydrocortisone (1)
Estra-1,3,5(10)-triene-3,6beta,17beta-triol (1)
D-Glucoheptose (1)
Flavin adenine degrad product (1)
(2R)-2-amino-3-phosphonopropanoic acid (1)
Biuret 1 (1)
Ribonic acid, gamma-lactone (1)
Acetylsalicylic Acid (1)
MALONAMIDE (1)
O-methylthreonine (1)
Trans,trans-Muconic acid (1)
Carbobenzyloxy-L-leucine degr (1)
2-Amino-2-norbornanecarboxylic acid (1)
N-cyclohexylformamide (1)
Citraconic acid degr (1)
Oxalacetic acid (1)
Hesperitin (1)
7-alpha-Hydroxycholesterol (1)
5-Dihydrocortisol (1)
Methyl Palmitoleate (1)
Cis-Phytol (1)
Hydroxyurea (1)
1,3-Cyclohexanedione (1)
Abietic Acid (1)
2-Butyne-1,4-diol (1)
Lactulose (1)
2,4,6-Trihydroxybenzophenone (1)
1,3-diaminopropane (1)
3-Hydroxypyridine (1)

First Public Date

2014 (93)
2024 (76)
2025 (68)
2023 (66)
2022 (64)
2021 (50)
2026 (47)
2020 (34)
2019 (25)
2018 (25)
2015 (24)
2017 (19)
2016 (16)
2013 (3)

Modification

2x(15)N labeled L-lysine (1)

Study status

Completed (1)

Study type

Transcription profiling by array (196)
RNA-seq of coding RNA (35)
RNA-seq of coding RNA from single cells (16)
ChIP-seq (11)
ATAC-seq (4)
Comparative genomic hybridization by array (3)
DNA-seq (3)
Animal - One-color microarray (2)
Transcription profiling by RT-PCR (2)
Other (2)
Proteomic profiling by array (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
Human - One-color microarray (1)
ChIP-chip by array (1)
MicroRNA profiling by array (1)
CUT&RUN (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of non coding RNA (1)
Interventional (1)

Release Date

2022 (157)
2020 (130)
2018 (117)
2021 (115)
2015 (115)
2019 (114)
2017 (113)
2023 (109)
2016 (108)
2025 (103)
2014 (102)
2024 (91)
2013 (80)
2011 (70)
2012 (64)
2010 (56)
2009 (34)
2008 (29)
2007 (24)
2026 (17)
2005 (12)
2006 (9)
2004 (9)
2003 (7)
2001 (6)
2000 (6)
2002 (5)
1999 (3)
1998 (2)

Lab affiliation

Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, UK (2)
Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czechia (1)
Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, CB2 0XY, UK (1)
Center of Excellence in Systems Biology, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand (1)
Chemistry (1)
Departamento de Ciências Biológicas, Laboratório de Enzimologia e Proteômica, Instituto de Ciencias Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto, Brasil (1)
Department of Biomedical Engineering University of Michigan, Ann Arbor 1119 Carl A. Gerstacker Building 2200 Bonisteel Boulevard Ann Arbor, MI 48109-2099 (1)
Department of Chemistry, Scripps Research, La Jolla, CA 92037, USA (1)
Department of Chemistry, University of Illinois Chicago, Chicago, USA (1)
Department of Medical Informatics and Statistics, BK21 Project, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Microbiology & Immunology, 2the Cancer Center, Medical College of Wisconsin Department of Medicine, Medical College of Wisconsin, Milwaukee, WI (1)
Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China. (1)
Department of Pharmaceutical Sciences, University of Illinois College of Pharmacy,Chicago,IL,USA Richard and Loan Hill Department of Biomedical Engineering, University of Illinois College of Engineering,Chicago, IL,USA University of Illinois Cancer Center,Chicago, IL,USA (1)
Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA (1)
Deputy Head (Research), Department of Biochemistry and Molecular Biology Head Immunoproteomics Laboratory Infection and Immunity Program Room 214, level 2, 15 Innovation Walk Monash Biomedicine Discovery Institute Monash University, Clayton Campus Clayton 3800 Victoria Australia (1)
Division of Cell Signalling and Immunology, College of Life Sciences, University of Dundee, Dundee, UK (1)
Erasmus MC Department of Neurology Clinical and Cancer Proteomics (1)
ICREA at ISGlobal Institute for Glbal Health, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain and IGTP Institut d'Investigació Germans Trias i Pujol, Badalona, Spain (1)
Indiana University School of Medicine (1)
Institute for Research in Immunology and Cancer, Department of Biochemistry, Department of Chemistry, Université de Montréal, Québec, Canada H3T 1J4 (1)
Institute of Agriculture and Natural Resources, Food Science and Technology, University of Nebraska-Lincoln, NE, United States (1)
Institute of Biomedical Sciences, Academia Sinica (1)
Laboraotry of RNA Biology and Functional Genomics, Insititue of Biochemistry and Biophysics Polish Academy od Sciences, Warsaw, Poland (1)
Laboratory of Regulatory Mechanisms in Immunity Institute of Carcinogenesis Federal State Budgetary Institution "N. N. Blokhin National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation (1)
Prabakaran lab, Department of Genetics, University of Cambridge, United Kingdom (1)
Professor, Bioengineering, Massachusetts Institute of Technology (1)
Proteomic Platform Necker, PPN-3P5, Structure Fédérative de Recherche SFR Necker US24, 75015, Paris, France (1)
Trinity College Dublin, Ireland (1)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (1)

Location

China (1)

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The innate and adaptive immune response to BCG stimulation in splenocytes taken from C57BL/6 mice

The aim of this experiment was to investigate differential gene expression in splenocytes stimulated with BCG from naïve and BCG vaccinated mice. The differences between naïve and BCG vaccinated mice might indicate the mechanisms by which BCG vaccination confers an enhanced ability of splenocytes fr...

ORGANISM(S): Mus musculus

2013-06-01 | E-GEOD-42090 | biostudies-arrayexpress

Expression profile of splenocytes with glucose-6-phosphate isomerase (GPI) induced arthritis

To explore TNF-related genes in GPI-induced arthritis, we performed GeneChip analysis using arthritic splenocytes and control-immunized splenocytes. Among the arrayed TNFalpha-related genes, TIARP mRNA was highly expressed in arthritic splenocytes, with levels exceeding more than 20-times the contro...

ORGANISM(S): Mus musculus

2010-03-03 | E-GEOD-17272 | biostudies-arrayexpress

Mouse splenocyte proteome - Proteome characterization of splenocytes from an Aβpp/ps-1 Alzheimer's disease model

Splenocytes from 14-month Alzheimer's Disease mouse model were separated with CD90.2 magetic beads into two cell subsets: CD90+ and CD90-. Proteome for these two subset were characterized with offline SCX-nanoLC-MS/MS. MS data was analyzed with Proteome Discoverer 1.3 software. MS/MS spectra ...

ORGANISM(S): Mus musculus (Mouse)

2014-01-31 | PXD000203 | Pride

Transcription profiling of mouse osteoclastogenic splenocytes

Effect of c-fos expression in osteoclastogenic splenocytes.

ORGANISM(S): Mus musculus

2008-06-15 | E-GEOD-676 | biostudies-arrayexpress

RNA-seq from mice CD4+CD25+ splenocytes

PRJNA858818 | ENA

Gene expression profiles of splenocytes of CD22DE12 transgenic mice

Splenocytes from nontransgenic control mice and transgenic mice were isolated and their gene expression profiles were compared to determine if the expression of the transgene results in any changes in regulation of gene expression. 12 differentially expressed genes were classified as the most discri...

ORGANISM(S): Mus musculus

2010-09-10 | E-GEOD-23998 | biostudies-arrayexpress

Transcription profiling of mouse splenic CD4+ cells after surgical induction of sepsis vs. controls reveals a distinct transcriptional response 6 hours after sepsis induction

Lymphocytes are adversely affected during sepsis. Some CD4+ splenocytes undergo apoptosis while others become Th2 polarized. The molecular determinants of these phenotypic changes are not known. Here we compare the transcriptional response of septic CD4 splenocytes to CD4 splenocytes from sham-manip...

ORGANISM(S): Mus musculus

2007-12-07 | E-GEOD-4479 | biostudies-arrayexpress

Single-cell ATAC-seq of mouse splenocytes

PRJEB26550 | ENA

Heme regulates the development of iron-recycling macrophages from monocytes (sorted splenocytes)

Splenic red pulp macrophages (RPM) degrade senescent erythrocytes and recycle heme-associated iron. The transcription factor Spic is selectively expressed by RPM and is required for their development, but the physiologic stimulus inducing Spic is unknown. Here, we report that Spic also regulated the...

ORGANISM(S): Mus musculus

2014-03-14 | E-GEOD-46984 | biostudies-arrayexpress

RNA-Seq analyses in miR-574-5p-transfected mouse splenocytes

PRJNA990654 | ENA

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