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ProteomicsPathogen and non-pathogen Spotted Fever Group Rickettsia trigger differential proteome signatures in macrophages
We have previously reported that Rickettsia conorii and Rickettsia montanensis have distinct intracellular fates within THP-1 macrophages, suggesting that the ability to proliferate within macrophages may be a distinguishable factor between pathogenic and non-pathogenic Spotted fever group (SFG) mem...
ORGANISM(S): Homo sapiens (Human) spotted fever group 
2019-02-16 | PXD010330 | Pride
Host-pathogen interactions Er quality control Rickettsia montanensis Macrophages Swath-ms Proteasome Infection Metabolic reprogramming Rickettsia conorii Spotted fever group rickettsia Protein processing pathways 
ProteomicsEndothelial cell proteomic response to Rickettsia conorii infection
Rickettsia conorii is the etiologic agent of Mediterranean spotted fever, a re-emerging disease with significant mortality. This obligate, gram-negative intracellular pathogen is transmitted via tick bites, resulting in disseminated vascular endothelial cell infection with vascular leakage. In the ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080856 | MassIVE
TranscriptomicsIntralesional host response within eschars in Mediterranean spotted fever
The host response within the eschar of inoculation during Mediterranean spotted fever (MSF) has been poorly studied. Our objective was to evaluate the host response by comparing transcriptional profiles of eschars to controls using a whole-genome microarray. Hierarchical clustering revealed a signat...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-32993 | biostudies-arrayexpress
GenomicsCutaneous Immunoprofile of Three Spotted Fever Group Rickettsiosis
Cutaneous Immunoprofile of Three Spotted Fever Group Rickettsiosis
PRJNA592903 | ENA
TranscriptomicsTranscription profiling of cultured human cells infected with African Swine Fever Virus (ASFV) to identify host genes required for replication of ASFV
African swine fever virus (ASFV) produces a fatal acute hemorrhagic fever in domesticated pigs that potentially is a worldwide economic threat. Using an expressed sequence tag (EST) library-based antisense method of random gene inactivation and a phenotypic screen for limitation of ASFV replication ...
ORGANISM(S): Homo sapiens 
2006-12-10 | E-SMDB-3898 | biostudies-arrayexpress
UnknownJapanese spotted fever, South Korea.
Not available
S-EPMC3291047 | biostudies-literature
UnknownNovel spotted fever group rickettsiosis, Brazil.
Not available
S-EPMC3322033 | biostudies-literature
UnknownSpotted fever diagnosis: Experience from a South Indian center.
Not available
S-EPMC8547824 | biostudies-literature
UnknownSpotted fever group rickettsiae (SFGR) detection in ticks following reported human case of Japanese spotted fever in Niigata Prefecture, Japan.
Not available
S-EPMC7844008 | biostudies-literature
UnknownRocky Mountain spotted fever, Panama.
Not available
S-EPMC3375809 | biostudies-literature
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