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Metabolomics13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis
Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spac...
2026-09-22 | MTBLS15760 | MetaboLights
Metabolomics13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis
Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spac...
2026-09-01 | MTBLS15516 | MetaboLights
Metabolomics13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis
Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spac...
2026-08-30 | MTBLS15501 | MetaboLights
Metabolomics13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis
Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spac...
2026-09-14 | MTBLS15663 | MetaboLights
Metabolomics13(S)-HODE Generated by Rhizopus microsporus var. rhizopodiformis Aggravates MASLD via the Elane-PAR2-SREBP-1c Axis
Abstract Objective:Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) poses a major public health challenge. Increasing data suggest a role of gut fungi in liver disease, yet their diversity and biological function in MASLD are still poorly understood. Methods:Internal transcribed spac...
2026-09-14 | MTBLS15643 | MetaboLights
ProteomicsHuman HeLa cells SREBP2-TurboID-MS
We employed the TurboID proximity labeling approach to map the interactome of SREBP2 with mass spectrometry-based proteomic analysis.
ORGANISM(S): Homo sapiens (Human) 
2025-03-22 | PXD061911 | Pride
Human Srebp2 Hela cells Turboid Ms 
TranscriptomicsNon-phosphorylated FTY720 induces apoptosis of human microglia by activating SREBP2
A synthetic analog of sphingosine named FTY720 (Fingolimod), phosphorylated by sphingosine kinase-2, interacts with sphingosine-1-phosphate (S1P) receptors expressed on various cells. FTY720 suppresses the disease activity of multiple sclerosis (MS) chiefly by inhibiting S1P-dependent egress of auto...
ORGANISM(S): Homo sapiens 
2011-04-16 | E-GEOD-28642 | biostudies-arrayexpress
GenomicsCarbon dioxide regulates cholesterol levels through SREBP2
Carbon dioxide regulates cholesterol levels through SREBP2
PRJNA804192 | ENA
GenomicsSREBP2 ChIP-seq analysis of SREBP2 regulated genes under FBS or cholesterol-depletion condition in HeLa cells
SREBP2 ChIP-seq analysis of SREBP2 regulated genes under FBS or cholesterol-depletion condition in HeLa cells
PRJNA1190434 | ENA
TranscriptomicsEffects of Intestine-specifc SREBP2 overactivation on gene expression in mouse jejnum
The active form of the SREBP2 transcription factor was specifically overexpressed in the intesitne. This was achieved by generating transgenic mouse model (designated as ISR2) in which the transgene represents the N-terminal active SREBP2 transcription factor driven by the villin promoter. In this p...
ORGANISM(S): Mus musculus 
2013-10-26 | E-GEOD-51736 | biostudies-arrayexpress
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