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TranscriptomicsPathway-based integrative analysis reveals a key role for the hexosamine biosynthetic pathway in castrate resistant prostate cancer with therapeutic implications
The development and progression of castrate resistant prostate cancer (CRPC), a lethal disease, is thought to be driven by multiple events. A hallmark of CRPC is the ability to evade the cytotoxic effects of anti-androgen therapy. Importantly, persistent androgen receptor (AR) signalling is thought ...
ORGANISM(S): Homo sapiens 
2015-04-03 | E-GEOD-67537 | biostudies-arrayexpress
TranscriptomicsExpression data from androgen treated LNCaP cells
Androgens are required for the development of normal prostate, and they are also linked to the development of prostate cancer. We used microarrays to understand the role of androgen in an androgen dependent, androgen receptor (AR) positive human metastatic cell line, LNCaP. LNCaP cells were grown in...
ORGANISM(S): Homo sapiens 
2009-12-29 | E-GEOD-17044 | biostudies-arrayexpress
UnknownLiver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Not available
S-EPMC5662191 | biostudies-literature
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
GenomicsImmune and Metabolic Features of Brain Metastases Melanoma (Cancer Discovery) Data Access Committee
Data Access Committee EGAC00001001216
EGAC00001001216 | EGA
ProteomicsLabel-free global proteome profiling of European American and African American bladder tumor patients.
Bladder cancer (BLCA) mortality is higher in African American (AA) patients compared to their European American (EA) counterparts, but the molecular mechanism underlying differences are unknown. . Thus, we performed proteomics analysis of AA and EA BLCA and identified higher mitochondrial OXPHOS spe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-08 | MSV000095559 | MassIVE
GenomicsWhole genome sequencing of Calamus brandisii - Female
Whole genome sequencing of Calamus brandisii - Female
PRJEB78638 | ENA
GenomicsWhole genome sequencing of Calamus brandisii
Whole genome sequencing of Calamus brandisii (Male)
PRJEB78439 | ENA
UnknownCareer intentions of medical students in the UK: a national, cross-sectional study (AIMS study).
Not available
S-EPMC10496670 | biostudies-literature
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