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The project is focused on the highly conserved sRNA scr5329 in Streptomyces coelicolor. A proteomics approach revealed that the sRNA regulates several metabolic enzymes, among them the Phosphoenolpyruvate-Carboxykinase (PEPCK), a key enzyme of the central carbon metabolism. The sRNA scr5239 promotes...
ORGANISM(S): Streptomyces coelicolor Bacteria 
2020-01-28 | PXD016811 | Pride
Transcriptome analysis of total RNA from the Rhodobacter sphaeroides 2.4.1 UdsC (sRNA) deletion mutant strain and UdsC (sRNA) overexpression strain under microaerobic growth conditions
In order to better define the global regulatory effects of the sRNA, GsrN, in Caulobacter crescentus during hyperosmotic stress, we submitted soluble lysates from a gsrN over-expression stain , as well as, a wild-type sample for LC-MS/MS analysis.
ORGANISM(S): Caulobacter crescentus CB15 
2019-11-12 | PXD010072 | Pride
The sRNA UdsC ist derived from the 3´ UTR of RSP_7527. To analyse the effect of the sRNA on the transcriptome of R. sphaeroides we performed the RNAseq analysis with a chromosomal knockout and an inducible overexpression of this sRNA.
ORGANISM(S): Cereibacter sphaeroides 
2022-12-28 | GSE216116 | GEO
The oral commensal Fusobacterium nucleatum can spread to extra-oral sites where it is associated with diverse pathologies including pre-term birth and cancer. Due to the evolutionary distance of F. nucleatum to other model bacteria, we lack a deeper understanding of RNA regulatory networks that allo...
ORGANISM(S): Fusobacterium nucleatum subsp. nucleatum ATCC 23726 
2024-02-08 | PXD047655 | Pride
In this study, transcriptomic analysis of the P. multocida strain VP161 revealed a putative sRNA with high identity to GcvB from Escherichia coli and Salmonella enterica serovar Typhimurium. High-throughput quantitative liquid proteomics was used to compare the proteomes of the P. multocida VP161 wi...
ORGANISM(S): Pasteurella multocida 
2019-11-12 | PXD007719 | Pride
Target identification of the cold stress induced sRNA CisR in Lactococcus lactis
In this experiment we compare the transcriptome profiles of a SmelC775 overexpression strain to a control strain overexpressing a control RNA (SmelC812) (Schlueter et al. 2010).
ORGANISM(S): Sinorhizobium meliloti 
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