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ProteomicsPhosphoproteomic analysis of mouse neurons with SRPK2 overexpression or knockdown
SRPK2 was identified as a presynaptic protein kinase involved in the regulation of neurotransmitter release. The phosphoproteome of mouse primary neurons was screened, under the conditions of SRPK2 overexpression and SRPK2 knockdown, to identify candidate substrates of SRPK2.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-14 | PXD016636 | Pride
Brain Mouse Phosphorylation Srpk2 
GenomicsSRPK2 CLIP-seq reveals direct RNA targets in breast cancer cells
SRPK2 CLIP-seq reveals direct RNA targets in breast cancer cells
PRJNA1493176 | ENA
GenomicsSRPK2 overexpression remodels the transcriptome landscape of triple-negative breast cancer cells
SRPK2 overexpression remodels the transcriptome landscape of triple-negative breast cancer cells
PRJNA1493197 | ENA
OtherSRPK2 CLIP-seq reveals direct RNA targets in breast cancer cells
SRPK2 (SRSF protein kinase 2) is a serine/arginine-rich protein-specific kinase that phosphorylates splicing factors and regulates alternative splicing. SRPK2 is highly expressed in breast cancer and associated with poor prognosis, and has been implicated in the post-transcriptional regulation of FA...
ORGANISM(S): Homo sapiens 
2026-07-15 | GSE338304 | GEO
TranscriptomicsSRPK2 overexpression remodels the transcriptome landscape of triple-negative breast cancer cells
SRPK2 (SRSF protein kinase 2) is a serine/arginine-rich protein-specific kinase that phosphorylates SR splicing factors and regulates pre-mRNA alternative splicing. SRPK2 is highly expressed in breast cancer and associated with poor prognosis. To characterize how SRPK2 remodels gene expression in tr...
ORGANISM(S): Homo sapiens 
2026-07-15 | GSE338307 | GEO
UnknownPost-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling.
Not available
S-EPMC5920692 | biostudies-literature
UnknownSRPK2 Mediates HBV Core Protein Phosphorylation and Capsid Assembly via Docking Interaction.
Not available
S-EPMC10878513 | biostudies-literature
UnknownImpaired expression of serine/arginine protein kinase 2 (SRPK2) affects melanoma progression.
Not available
S-EPMC9537589 | biostudies-literature
UnknownDownregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer.
Not available
S-EPMC6945924 | biostudies-literature
UnknownAn IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer.
Not available
S-EPMC9469522 | biostudies-literature
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