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ProteomicsPhosphoproteomic analysis of control and Ste20-like kinase (Slk) knockdown cortical neurons
The Ste20-like kinase (Slk) is a serine/threonine kinase that regulates cytoskeletal organization, apoptosis, and cell polarity in non-neuronal cells. In neurons, Slk guides dendrite morphogenesis and inhibitory synapse stability, thereby controlling excitation-inhibition balance. We compared the ph...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-06 | PXD072739 | Pride
Tmt Knockdown Phosphoproteomics Cortical neurons Ste20-like kinase 
GenomicsExon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
PRJNA1273951 | ENA
UnknownActivation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD.
Not available
S-EPMC162144 | biostudies-literature
UnknownRegulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3.
Not available
S-EPMC1316964 | biostudies-literature
ProteomicsIdentification of a Ste20-like kinase-dependent network orchestrating cytoskeletal and synaptic development of cortical neurons. Untargeted phosphorylation analysis
The Ste20-like kinase (Slk) is a serine/threonine kinase that regulates cytoskeletal organization, apoptosis, and cell polarity in non-neuronal cells. In neurons, Slk guides dendrite morphogenesis and inhibitory synapse stability, controlling excitation-inhibition balance through parvalbumin interne...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-10-02 | PXD073661 | Pride
Germinal center kinases Kinase signaling Affinity purification-mass spectrometry Lc/ms Protein-protein interactions Phosphoproteomics 
UnknownSte20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes.
Not available
S-EPMC10068952 | biostudies-literature
UnknownThe mammalian Ste20-like kinase 2 (Mst2) modulates stress-induced cardiac hypertrophy.
Not available
S-EPMC4148857 | biostudies-literature
UnknownMammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment.
Not available
S-EPMC4047884 | biostudies-literature
UnknownCircuit-selective cell-autonomous regulation of inhibition in pyramidal neurons by Ste20-like kinase.
Not available
S-EPMC9756112 | biostudies-literature
TranscriptomicsExon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
Dysregulated RNA splicing is activated in tumors; however, the metabolic landscape and consequent implications of this process remain largely unexplored. In this study, we identified exon skipping in Ste20-like kinase (SLK), resulting in a variant isoform of SLK (SLKv), which promotes glycolysis in ...
ORGANISM(S): Homo sapiens 
2025-06-17 | GSE299345 | GEO
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