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4D-FastDIA quantitative phosphorylation modification omics analysis before and after expression of Salmonella effector SteC in RAW264.7 cell

The Salmonella effector SteC is the only protein kinase encoded by Salmonella pathogenicity island 2 that is secreted through the type III secretion system. SteC is known to trigger actin rearrangement via the phosphorylated MEK pathway, and our previous experiments demonstrated that the migration p...

ORGANISM(S): Mus musculus (Mouse)

2024-02-22 | PXD042038 | Pride

Salmonella effector kinase SteC is activated by host-mediated phosphorylation

The pathogen Salmonella, which causes significant human morbidity and mortality, encodes an effector kinase, SteC, which mediates actin polymerisation and cell migration of the infected cell. Analysis of the sequence and predicted structure alongside canonical eukaryotic serine-threonine kinases rai...

ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. T000240

2026-06-12 | PXD061217 | Pride

Bacterial kinase Hdx Stec Effector Phosphorylation Salmonella Host-pathogen interactions Kinase regulation Non-rd kinase

National surveillance of STEC at the Belgium National Reference Centre for STEC

National surveillance of STEC at the Belgian National Reference Centre for STEC

PRJEB61522 | ENA

Molecular surveillance of STEC

Routine surveillance of STEC at the Belgian NRC STEC

PRJEB54005 | ENA

DiSCoVer-PIWet-Poland-STEC

DiSCoVer-PIWet-STEC

PRJEB57392 | ENA