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The Salmonella effector SteC is the only protein kinase encoded by Salmonella pathogenicity island 2 that is secreted through the type III secretion system. SteC is known to trigger actin rearrangement via the phosphorylated MEK pathway, and our previous experiments demonstrated that the migration p...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-22 | PXD042038 | Pride
The 4D-FastDIA quantitative proteome of Brucella treated with B12
ORGANISM(S): Brucella Suis Bv. 1 Str. S2 
2024-01-22 | PXD048784 |
This study aims to conduct quantitative proteomics analysis on 9 mouse myocardial tissue samples, which are divided into 3 groups with 3 biological replicates in each group, using the 4D-FastDIA technique.
ORGANISM(S): Mus Musculus 
This project performs quantitative proteomics analysis on 9 human pluripotent stem cells (hPSCs) by using the 4D-FastDIA technology. There are 3 groups, and each group has 3 biological replicates. The goal is to map the proteome of hPSCs, which helps to deeply investigate their molecular mechanisms ...
ORGANISM(S): Homo Sapiens 
In this study, we identified a significant lactylation modification at lysine 193 (K193) of STAT1 in gastric cancer tissues through an integrated proteomic and lysine lactylome analysis. Functional assays revealed that the loss of STAT1-K193 lactylation (STAT1-K193la) markedly suppresses gastric can...
ORGANISM(S): Homo sapiens (Human) 
2025-09-05 | PXD065104 | Pride
The process of iPSC reprogramming involves various critical events such as somatic gene shutdown, mesenchymal-epithelial transition (MET), metabolism reprogramming, and epigenetic rewiring. These events interweave and influence each other leading to the formation of the iPSC reprogramming network, t...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD043547 | Pride
Extracellular vesicles (EVs) are known to impact microbial metabolic activities, but their specific role in Mn reduction remains arcane. We aim to uncover the underlying mechanisms by which EVs facilitate this process. EVs from Shewanella oneidensis MR-1, the model strain for extracellular electron ...
ORGANISM(S): Shewanella Oneidensis Mr-1 
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