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ProteomicsSlowing prion disease via M1 muscarinic receptors is associated with reduced neuroinflammation and down-regulation of neurodegenerative disease markers
Currently there are no treatments that can slow or halt the progression of dementia’s including Alzheimer’s disease. Here we investigate the possibility that activation of the M1-muscarinic receptor (M1-receptor), which is highly expressed in the brain and that shows pro-cognitive properties, might ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-14 | PXD025561 | Pride
G protein-coupled receptor Alzheimer’s disease Neuroinflammation Warwick_rtp Positive allosteric modulators Transcriptomic Prion disease Proteomic Neurodegeneration Neurodegenerative disease M1 muscarinic acetylcholine receptor 
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