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Wildtype and Mt1(-/-)Mt2(-/-) double knockout 129S1/SvImJ strain mouse lungs were compared in their response to nickel aerosol exposure at 3, 8, 24, 48, and 72 hrs.
ORGANISM(S): Mus musculus 
Pioneer colonization of the gastrointestinal tract by bacteria is thought to have major influence on neonatal tissue development. Previous studies have shown in ovo inoculation of embryos with saline (S), species of Citrobacter (C, C2), or lactic-acid bacteria (LAB) resulted in an altered microbiome...
ORGANISM(S): Gallus gallus (Chicken) 
2020-01-09 | PXD015504 | Pride
Sexual development in mammals is based on a complicated and delicate network of genes and hormones that have to collaborate in a precise manner. The dark side of this pathway is represented by pathological conditions, wherein sexual development does not occur properly either in the XX and the XY bac...
ORGANISM(S): Canis lupus familiaris 
Transcriptional profiling of non-CML CD34+ cells to understand the response of non-CML stem cells to an EZH2 inhibitor, GSK343.
ORGANISM(S): Homo sapiens 
Quiescent and dividing hemopoietic stem cells (HSC) display marked differences in their ability to move between the peripheral circulation and the bone marrow. Specifically, long-term engraftment potential predominantly resides in the quiescent HSC subfraction, and G-CSF mobilization results in the ...
ORGANISM(S): Homo sapiens 
Transcriptional profiling of four cell populations to understanding chronic myeloid leukaemia in humans. The populations are normal haematopoietic stem cells (HSC), normal progenitor cells (HPC), CML stem cells (LSC) and CML progenitor cells (LPC).
ORGANISM(S): Homo sapiens 
Transcriptional profiling by array of CML CD34+ cells to understand the response of chronic myeloid leukaemia stem cells to an EZH2 inhibitor, GSK343.
ORGANISM(S): Homo sapiens 
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