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ProteomicsProteomics on colorectal cancer MCTS upon OXPHOS inhibition
Previous high throughput gene expression profiling combined with a HCT116 colon cancer tumor spheroid-based drug-screening assay identified context-dependent treatment responses to OXPHOS inhibitors resulting in a shunting towards the mevalonate pathway. To complement these findings with a character...
ORGANISM(S): Homo sapiens (Human) 
2020-07-29 | PXD016495 | Pride
Colon cancer Oxphos Proteomics Spheroids Energy metabolism 
MetabolomicsIntegration of magnetic resonance imaging and protein and metabolite CSF measurements to enable early diagnosis of secondary progressive multiple sclerosis

Molecular networks in neurological diseases are complex. Despite this fact, contemporary biomarkers are in most cases interpreted in isolation, leading to a significant loss of information and power. We present an analytical approach to scrutinize and combine information from biomarkers originati...

2018-08-13 | MTBLS558 | MetaboLights
ProteomicsA synthetically methylotrophic Escherichia coli as a chassis for bioproduction
Proteome characterization of three E. coli strains: a methanol-dependent strain (MEvo1-0) and two synthetically methylotrophic strains (MEcoli_ref_1, MEcoli_ref_2)
ORGANISM(S): Escherichia coli 
2024-02-08 | PXD046243 | Pride
Synthetic biology Metabolic engineering Synthetic methylotrophy Biotechnology E. coli 
UnknownEffect of dulaglutide in promoting abstinence during smoking cessation: a single-centre, randomized, double-blind, placebo-controlled, parallel group trial.
Not available
S-EPMC9981899 | biostudies-literature
UnknownEffect of dulaglutide in promoting abstinence during smoking cessation: 12-month follow-up of a single-centre, randomised, double-blind, placebo-controlled, parallel group trial.
Not available
S-EPMC10873660 | biostudies-literature
MetabolomicsDisease phenotype prediction in multiple sclerosis

Progressive multiple sclerosis (PMS) is currently diagnosed retrospectively. Here, we work towards a set of biomarkers that could assist in early diagnosis of PMS. A selection of cerebrospinal fluid metabolites (n=15) was shown to differentiate between PMS and its preceding phenotype in an indepe...

2023-05-31 | MTBLS1464 | MetaboLights
UnknownIndividual-patient meta-analysis of three randomized trials comparing endovascular versus open repair for ruptured abdominal aortic aneurysm.
Not available
S-EPMC4744980 | biostudies-literature
UnknownValue of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm.
Not available
S-EPMC6055637 | biostudies-literature
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