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UnknownDose-Duration Reciprocity for G protein activation: Modulation of kinase to substrate ratio alters cell signaling.
Not available
S-EPMC5747438 | biostudies-literature
UnknownA target trial emulation of dexmedetomidine to treat agitation in the intensive care unit.
Not available
S-EPMC11991816 | biostudies-literature
TranscriptomicsDissecting the in vivo metabolic potential of two human gut acetogens.
Fermenting microbial communities generate hydrogen: its removal through production of acetate, methane, or hydrogen sulfide modulates the efficiency of energy extraction from available nutrients in many ecosystems. We noted that pathway components for acetogenesis are more abundantly and consistentl...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-21 | E-GEOD-21906 | biostudies-arrayexpress
TranscriptomicsApplication of a translational profiling approach for the comparative analysis of CNS cell types.
Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturb...
ORGANISM(S): Mus musculus 
2008-11-14 | E-GEOD-13379 | biostudies-arrayexpress
UnknownDynamic Glucose-Enhanced (DGE) MRI: Translation to Human Scanning and First Results in Glioma Patients.
Not available
S-EPMC4710854 | biostudies-literature
ProteomicsLocalised protein expression changes in different regions of human Alzheimer’s brain correlate with disease severity - Hippocampus
Human brain tissue was obtained from the New Zealand Brain Bank from donors with Alzheimer's disease (AD) or age-matched controls (n=9/group). Mean post mortem delays were ~12h. Six distinct brain regions were dissected, Hippocampus, Cingulate Gyrus, Entorhinal Cortex (severely affected), Motor and ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD008739 | Pride
Human Dementia Brain Hippocampus Alzheimer’s Itraq 
ProteomicsLocalised protein expression changes in different regions of human Alzheimer’s brain correlate with disease severity - Cerebellum
Human brain tissue was obtained from the New Zealand Brain Bank from donors with Alzheimer's disease (AD) or age-matched controls (n=9/group). Mean post mortem delays were ~12h. Six distinct brain regions were dissected, Hippocampus, Cingulate Gyrus, Entorhinal Cortex (severely affected), Motor and ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD008755 | Pride
Human Dementia Brain Cerebellum Alzheimer’s Itraq 
ProteomicsLocalised protein expression changes in different regions of human Alzheimer’s brain correlate with disease severity - Sensory Cortex
Alzheimer's disease (AD) or age-matched controls (n=9/group). Mean post mortem delays were ~12h. Six distinct brain regions were dissected, Hippocampus, Cingulate Gyrus, Entorhinal Cortex (severely affected), Motor and Sensory Cortex (less affected) and Cerebellum (spared). Protein was extracted fro...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD008753 | Pride
Human Dementia Brain Sensory cortex Alzheimer’s Itraq 
UnknownSubcortical surface morphometry in substance dependence: An ENIGMA addiction working group study.
Not available
S-EPMC7237314 | biostudies-literature
UnknownWhite matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group.
Not available
S-EPMC7055351 | biostudies-literature
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