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TranscriptomicsPlasmodium falciparum treated with cyclohexylamine
Transcriptional profiling of P. falciparum cultures treated with cyclohexylamine over time (18, 25 and 30 hours post invasion) A control experiment was also set up in which P. falciparum was not treated with cyclohexylamine, and samples were taken at 18, 25 and 30 h post invasion). Background Plasm...
ORGANISM(S): Plasmodium falciparum 
2010-04-19 | E-GEOD-18075 | biostudies-arrayexpress
ProteomicsAssessing the dynamics and macromolecular interactions of the intrinsically disordered protein YY1
YY1 is a ubiquitously expressed, intrinsically disordered transcription factor involved in neural development. The oligomeric state of YY1 varies depending on the environment. These changes may alter its DNA binding ability and hence its transcriptional activity. In addition to its oligomeric state,...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD038431 | Pride
Yy1 Intrinsic disorder Foxp2 Dna binding Protein-protein interactions 
ProteomicsSWATH-MS based proteomic profiling of Pancreatic Ductal Adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways
Pancreatic cancer accounts for 2.8% of new cancer cases worldwide and is projected to become by 2030 the second leading cause of cancer-related deaths. Patients of African ancestry appear to be at an increased risk for pancreatic ductal adenocarcinoma (PDAC), with worse severity and outcomes. The pu...
ORGANISM(S): Homo sapiens (Human) 
2020-09-30 | PXD019549 | Pride
Pancreatic cancer Extracellular matrix Swath-ms 
ProteomicsMag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome
Membrane-bound particles in plasma are composed of exosomes, microvesicles, and apoptotic bodies and represent ~1-2% of the total protein composition. Proteomic interrogation of this subset of plasma proteins augments the representation of tissue-specific proteins, representing a “liquid biopsy,” wh...
ORGANISM(S): Homo Sapiens 
PXD042947 | panorama
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