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TranscriptomicsCross-regulation between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa
Two-component systems (TCS) serve as basic stimulus-response coupling mechanisms to allow organisms to sense and respond to a large variety of environmental conditions. In the opportunistic pathogen Pseudomonas aeruginosa, more than 100 genes encode TCS components. To avoid unwanted cross-talk betwe...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2015-06-08 | E-GEOD-64056 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila mechanoreceptor-rich tissue compared mechanoreceptor-poor tissue shows DCX-EMAPis required for mechanoreception in sensory cilia
Determining which genes are expressed in mechanoreceptor-rich tissue (pedicel) compared mechanoreceptor-poor tissue (capitellum) and a neuronal subtraction control (thoracic ganglion) in Drosophila melanogaster
ORGANISM(S): Drosophila melanogaster 
2009-05-01 | E-MEXP-1921 | biostudies-arrayexpress
TranscriptomicsUbiquitin-dependent turnover of MYC promotes loading of the PAF complex on RNA Polymerase II to drive transcriptional elongation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-70009 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat colon from animals fed cellulose vs FOS diets and infected with Salmonella
To increase our knowledge of the effects of Fructo oligosaccharides (FOS) on Salmonella infection in fats, a controlle rat infection study was performed. Two groups of 12 rats were adapted for 14 days to a cellulose diet and one group of 12 rats to a FOS diet. One cellulose-fed group and the FOS-fed...
ORGANISM(S): Rattus norvegicus 
2008-06-15 | E-GEOD-7472 | biostudies-arrayexpress
TranscriptomicsA MYC-driven change in mitochondrial dynamics limits stem cell properties of mammary epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-10-28 | E-GEOD-66263 | biostudies-arrayexpress
TranscriptomicsComparative transcriptome analysis of Saccharomyces cerevisiae wild type and M-NM-^Tasc1 strain
Asc1p and its essential orthologues in higher eukaryotes, as e.g. RACK1 in mammals, are involved in several distinct cellular signaling processes, but the implications of a total deletion have never been assessed in a comprehensive genome-wide manner. This study reveals the major cellular processes ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-30 | E-GEOD-34286 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Trypanosoma bruceii DHH1 wild type from pLEW100 for 24 hours
Induction of the expression of the DHH1 wild type from pLEW100 for 24 hours (M-1 24 hours Tetracycline). Non-induced cells were used as control.
ORGANISM(S): Trypanosoma brucei 
2010-01-01 | E-MEXP-2025 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Trypanosoma brucei DHH1 DEAD:DQAD mutant from pLEW100 for 24 hours
Induction of the expression of the DHH1 DEAD:DQAD mutant from pLEW100 for 24 hours (thus, M-1 24 hours
Tetracycline). Uninduced cells were used as control.
ORGANISM(S): Trypanosoma brucei 
2010-01-01 | E-MEXP-2026 | biostudies-arrayexpress
TranscriptomicsRNA-seq study of major P.aeruginosa PA14 transcription factors
Gene regulation via transcription factors influences the metabolic, adaptive and pathogenic capabilities of the organism. We report the transcriptomes of the mutants of six major P. aeruginosa PA14 trancription factors - RhlR, LasR, Anr, GacA, FleQ and CbrB. The P. aeruginosa PA14 transposon mutants...
ORGANISM(S): Pseudomonas aeruginosa 
2016-03-01 | E-GEOD-55328 | biostudies-arrayexpress
TranscriptomicsUbiquitin-dependent turnover of MYC promotes loading of the PAF complex on RNA Polymerase II to drive transcriptional elongation (RNA-seq)
The MYC transcription factor is an unstable protein and its turnover is controlled by the ubiquitin system. Ubiquitination enhances MYC-dependent transactivation, but the underlying mechanism remains unresolved. Here we show that proteasomal turnover of MYC is dispensable for recruitment of RNA poly...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-70000 | biostudies-arrayexpress
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