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MetabolomicsCancer-cell-secreted exosomal miR-105 promotes tumour growth through the Myc-dependent metabolic reprogramming of stromal cells
Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and to buffer the negative effects of environmental changes. Extracellular miRNAs have been recently implicated in the intercellular crosstalk. Here we show a mechanistic model involving breast-canc...
2018-07-10 | MTBLS626 | MetaboLights
TranscriptomicsUterine stromal cell_cultured with uNK conditioned Medium
The endometrium contains a distinct population of immune cells consisting of 70% natural killer (NK) cells that undergo cyclic changes during the menstrual cycle. However, how these uterine NK (uNK) cells interact with uterine stromal cells (SC) remains unclear. We therefore investigated the paracri...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-9718 | biostudies-arrayexpress
GenomicsSingle-cell sequencing of adipose-derived mesenchymal stromal cells and dermal fibroblasts
Single-cell sequencing of adipose-derived mesenchymal stromal cells and fibroblasts.
EGAS00001006954 | EGA
ProteomicsProteomics of cardiac stromal cells and dermal fibroblasts secretomes
The proteomics characterization of the secretomes as well as the evaluation of their potential to induce cell and tissue responses are widely used strategies. Here are presented the mass spectrometry data of the resident cardiac stromal cells (CRSC) and dermal fibroblasts secretomes, which enables t...
ORGANISM(S): Homo sapiens (Human) 
2022-02-07 | PXD026451 | Pride
Dermal fibroblasts Cardiac stromal cells Secretome Lc-ms/ms 
TranscriptomicsCervical carcinoma-associated fibroblasts are DNA diploid and do not show evidence for somatic genetic alterations
Cancer-associated fibroblasts (CAFs) have been recognized as important contributors to cancer development and progression. However, opposing evidence has been published whether CAFs, in addition to epigenetic, also undergo somatic genetic alterations and whether these changes contribute to carcinoge...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-GEOD-29143 | biostudies-arrayexpress
GenomicsComparative transcriptomics of endometrial stromal fibroblasts
Comparative transcriptomics of endometrial stromal fibroblasts
PRJNA280591 | ENA
ProteomicsProteomic analysis of extracellular vesicles and conditioned medium from human Adipose-derived Stem/Stromal Cells and Dermal Fibroblasts
Conditioned medium (CM) and extracellular vesicles (EV) from human Adipose-derived Stem/stromal cells (ASC) and Dermal fibroblasts (DF) can represent valid cell substitutes in regenerative medicine and other therapeutic applications. Whether one of the two cell products should be preferred over the ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD020219 | Pride
Adipose-derived stromal cells Label-free quantitative proteomics Extracellular vesicles Dermal fibroblasts Conditioned medium Secretome 
TranscriptomicsTranscriptional profiling by array of human head and neck squamous cell carcinoma to study the correlation between galectin-1 upregulation and the presence of SMA positive cancer-associated fibroblasts
In this study, we set the presence of smooth muscle actin (SMA)-positive cancer-associated fibroblasts (CAFs) in relation to galectin-1 and its in vivo competitor (galectin-3). In squamous cell carcinomas of head and neck, upregulation of galectin-1 presence is highly significantly correlated to pre...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MTAB-850 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary cultures from mouse cornea vs those of the adult and 10-day postnatal mouse cornea to elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells
To elucidate biological processes underlying the keratocyte, fibroblast, and myofibroblast phenotypes of corneal stromal cells, the gene expression patterns of these primary cultures from mouse cornea were compared with those of the adult and 10-day postnatal mouse cornea.
ORGANISM(S): Mus musculus 
2007-10-31 | E-GEOD-1867 | biostudies-arrayexpress
GenomicsTranscriptomic responses to hypoxia in endometrial stromal fibroblasts and decidual stromal cells
Transcriptomic responses to hypoxia in endometrial stromal fibroblasts and decidual stromal cells
PRJNA437464 | ENA
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