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UnknownInhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation.
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S-EPMC3148313 | biostudies-literature
TranscriptomicsSpecies-specific factors mediate extensive heterogeneity of mRNA 3' ends in yeasts
Most eukaryotic genes express mRNAs with alternative polyadenylation sites at their 3’ ends. Here we show that polyadenylated 3’ termini in three yeast species (S. cerevisiae, K. lactis, D. hansenii) are remarkably heterogeneous. Instead of a few discrete 3’ ends, the average yeast gene has an “en...
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-03 | E-GEOD-47661 | biostudies-arrayexpress
GenomicsSaccharomyces cerevisiae Sko1-HA strain MAP37, W303-1A background
These three replicates were analyzed in "Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae. ", by Proft M, Gibbons FD, Copeland M, Roth FP, Struhl K; published in Eukaryot Cell. 2005 Aug;4(8):1343-5...
ORGANISM(S): Saccharomyces cerevisiae 
2005-09-21 | GSE3335 | GEO
GenomicsSaccharomyces cerevisiae
Saccharomyces cerevisiae Sko1-HA strain MAP37, W303-1A background
PRJNA93241 | ENA
GenomicsGenome-wide mapping of Jun binding site (K562)
Proto-oncogene c-jun is a leucine-zipper containing transcription factor which has a DNA binding domain and a transactivation domain. Jun dimerizes with another transcription factor Fos to form AP1 transcription factor. The AP-1 complex has been implicated in transformation and progression of cancer...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-GEOD-19545 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae response to Oxygen, Heme and Cobalt
Yeast cell growth and treatment:; Yeast strains used were L51 (MATa, ura3-52, leu2-3, 112, his4-519, ade1-100, trp1::HisG, hap1::LEU2) and MHY100 (MATa, ura3-52, leu2-3, 112, his4-519, ade1-100, hem1-delta100). L51 was used for studies of oxygen regulation, and MHY100 was used for studies of heme r...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-25 | E-GEOD-8343 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Fos binding site (K562)
Proto-oncogene c-Fos is a leucine-zipper containing transcription factor which has a DNA binding domain and a transactivation domain. Fos dimerizes with another transcription factor Jun to form AP1 transcription factor. The AP-1 complex has been implicated in transformation and progression of cancer...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-GEOD-19546 | biostudies-arrayexpress
TranscriptomicsReplication and active demethylation represent partially overlapping mechanisms for erasure of H3K4me3 in budding yeast
Histone modifications affect DNA-templated processes ranging from transcription to genomic replication. In this study, we examine the cell cycle dynamics of the trimethylated form of histone H3 lysine 4 (H3K4me3), a mark of active chromatin that is viewed as “long-lived” [1], and that is involved in...
ORGANISM(S): Saccharomyces cerevisiae 
2009-01-28 | GSE14565 | GEO
GenomicsMapping Novel Chromatin Regions Using Sono-Seq
We found that sonication of crosslinked chromatin produces breaks at non-random sites in DNA and can be used to map sites of high chromatin accessibility when combined with high-throughput tag sequencing using the GA II platform from Illumina. This technique, which we named Sono-Seq, can be a simple...
ORGANISM(S): Homo sapiens 
2008-12-18 | E-GEOD-14022 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Myc binding site (K562)
Proto-oncogene c-myc encodes a bHLH leucine-zipper containing transcription factor which has a DNA binding domain and a transactivation domain. Myc can dimerize with other factors like Max, Mad, Mnt and Miz and can influence transcription of genes. The c-myc oncogene contributes to the genesis of a ...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-GEOD-19547 | biostudies-arrayexpress
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