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ProteomicsHDX-MS Analysis of RORg:RORE:SRC3 Complexes
The retinoic acid receptor-related orphan receptor γ (RORγ) is a ligand-dependent transcription factor that both underpins metabolic and immune functions and provides vantage to manipulate those processes pharmacologically. Despite its importance, our understanding of the ligand-dependent activities...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025765 | Pride
Protein-dna interaction Rorg Rorg response elements Hydrogen deuterium exchange mass spectrometry Protein-protein interaction Src3 
ProteomicsXL-MS Analysis of Recombinant GPR158:RGS7:Gb5 Complex in Detergent Micelles
GPR158 is widely expressed in the brain and have been implicated in depression, cognition, mood and several cancers. GPR158 is also involved in retinal photoreceptor signaling along with it involvement in synaptic organization. GPR158 interact with G-protein regulator-RGS7 and brings it to plasma me...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026603 | Pride
Rgs7 Orphan gpcr Gb5 Gpcr-rgs complex Membrane protein complex Gpr158 G-protein coupled receptor Chemical crosslinking 
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