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ProteomicsIdentify the proteins interacting with STX17
To identify the specific proteins interacting with STX17, HEK293T cells stably expressing Flag-STX17 were lysed and immunoprecipitated with anti-Flag antibody, and eluted for Commassie blue staining and then subjected to mass spectrometric analysis.
ORGANISM(S): Homo sapiens (Human) 
2023-06-24 | PXD041897 | Pride
Stx17 Immunoprecipitation assays 
Proteomicsinteraction proteins of human STX17 WT and K254R
finding the different proteins of STX17 WT and STX17 K254R mutant
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD062683 | Pride
Interaction protein Acetylation Stx17 Human 
Proteomicsacetylation modification of human STX17-LC MS
finding the acetylation modified sites of human STX17 before and after starvation
ORGANISM(S): Homo sapiens (Human) 
2026-04-01 | PXD062534 | Pride
Autophagy Acetylation Stx17 Human 
ProteomicsULK phosphorylation of STX17 controls autophagosome maturation via FLNA
Autophagy is a conserved and tightly regulated intracellular quality control pathway. ULK is a key kinase in autophagy initiation, but whether ULK kinase activity also participates in late stages of autophagy remains unknown. Here, we found that the autophagosomal SNARE protein, STX17, is phosphoryl...
ORGANISM(S): Homo Sapiens 
2023-06-18 | PXD043082 |
ProteomicsSerine ubiquitination of SNAREs generates bacterial vacuoles and prevents their lysosomal fusion
Here we show that Legionella SidE effectors mediate phosphoribosyl-linked serine ubiquitination (PR-Ub) of the autophagic SNARE proteins STX17 and SNAP29. On the one hand, PR-Ub modification of STX17 enhances its interaction with ATG14L, which drives the recruitment of ER membranes to the bacterial ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-14 | PXD058184 | Pride
Legionella pneumophila Xenophagy Syntaxin17 Ubiquitin Autophagy 
GenomicsDownregulation of microRNA-300-3p promotes steatosis-to-MASH progression by regulating STX17
Downregulation of microRNA-300-3p promotes steatosis-to-MASH progression by regulating STX17
PRJNA1453935 | ENA
GenomicsDownregulation of microRNA-300-3p promotes steatosis-to-MASH progression by regulating STX17
Background & aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) ranges from simple steatosis (MAFL) to metabolic dysfunction-associated steatohepatitis (MASH). With the complex etiological factors associated with MAFLD, the molecular mechanism underlying the progression from steatosi...
ORGANISM(S): Mus musculus 
2026-05-20 | GSE328114 | GEO
UnknownAcetylation of STX17 (syntaxin 17) controls autophagosome maturation.
Not available
S-EPMC8143222 | biostudies-literature
UnknownULK phosphorylation of STX17 controls autophagosome maturation via FLNA.
Not available
S-EPMC10316704 | biostudies-literature
UnknownMechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.
Not available
S-EPMC5839791 | biostudies-literature
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