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ProteomicsQuantitative analysis to the subcellular proteome in response to cathepsin D knockdown in HeLa cells
Cathepsin D is reportedly to be closely associated with tumor development, migration and invasion, but its pathological mechanism is not fully elucidated. We aimed to evaluate phenotypic changes and molecular events in response to cathepsin D knockdown. Lowering endogenous cathepsin D abundance (CR)...
ORGANISM(S): Homo sapiens (Human) 
2015-12-17 | PXD002844 | Pride
Cytosol Lysosome Silac Nucleus Subcellular fractionation 
UnknownCharacterization of the Key Aroma Compounds in Dong Ding Oolong Tea by Application of the Sensomics Approach.
Not available
S-EPMC10486682 | biostudies-literature
UnknownExtracellular vesicles extracted from young donor serum attenuate inflammaging via partially rejuvenating aged T-cell immunotolerance.
Not available
S-EPMC6181631 | biostudies-literature
TranscriptomicsDong M. oryzae MAPK pathway mutants
Gene expression profiling in MAPK-related mutants of Magnaporthe oryzae
ORGANISM(S): Magnaporthe oryzae 
2012-06-19 | E-MEXP-3658 | biostudies-arrayexpress
TranscriptomicsThe role of the Ras- and cAMP-signaling pathways in stress response and sterol biosynthesis in Cryptococcus neoformans
The cAMP-pathway plays a central role in regulation of growth, differentiation, and virulence of human pathogenic fungi, including Cryptococcus neoformans. Three major upstream signaling regulators of the adenylyl cyclase (Cac1), Ras, Aca1 (Adenylyl cyclase-associated protein 1) and G-alpha subunit ...
ORGANISM(S): Cryptococcus neoformans var. grubii H99 
2010-05-22 | E-GEOD-17338 | biostudies-arrayexpress
MetabolomicsComparative characterization of the infant gut microbiome and their maternal lineage by a multi-omics approach

The human gut microbiome establishes and matures during infancy, and dysregulation at this stage may lead to pathologies later in life. We conducted a multi-omics study comprising three generations of family members to investigate the early development of the gut microbiota. Fecal samples from 20...

2024-03-07 | MTBLS7670 | MetaboLights
UnknownLowering Endogenous Cathepsin D Abundance Results in Reactive Oxygen Species Accumulation and Cell Senescence.
Not available
S-EPMC5500756 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis thaliana wild type and ARR7 plants to identify cytokine response genes at two different time points
to identify regulated genes in response to cytokinin in wild-type and 35S:ARR7 plants using the Affymetrix ATH1 full genome array.
ORGANISM(S): Arabidopsis thaliana 
2006-11-01 | E-ATMX-3 | biostudies-arrayexpress
UnknownPredictive value of relative fat mass algorithm for incident hypertension: a 6-year prospective study in Chinese population.
Not available
S-EPMC7569915 | biostudies-literature
UnknownFTO-dependent m<sup>6</sup>A Demethylation Activates Mxd1 To Enhance Vitamin D-induced Suppression of Neuroinflammation Via PTEN/AKT/PGC-1α Signaling Pathways in Microglia.
Not available
S-EPMC12916930 | biostudies-literature
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