Sort   by:  
 Page size 
UnknownThe power of lived experience in optimizing US policymakers' engagement with substance use research: A series of rapid-cycle randomized controlled trials.
Not available
S-EPMC11621502 | biostudies-literature
UnknownHuman Umbilical Cord Mesenchymal Stem Cells Preserve Adult Newborn Neurons and Reduce Neurological Injury after Cerebral Ischemia by Reducing the Number of Hypertrophic Microglia/Macrophages.
Not available
S-EPMC5784525 | biostudies-literature
TranscriptomicsEffect of estradiol (E2) exposure and KMT2B knockdown on gene expression in MCF-7 cells
MCF-7 is an estrogen receptor-positive breast cancer cell line. This experiment is designed to study (1) the effect of estradiol (E2) exposure and (2) lysine methyltransferase 2B (KMT2B) knockdown in MCF-7 cells. Cells were grown for 72 hours prior to treatment with vehicle or 10 nM E2 for 4 and 24 ...
ORGANISM(S): Homo sapiens 
2017-01-30 | E-MTAB-4923 | biostudies-arrayexpress
GenomicsMNase and HpaII sensitivity assays in MCF7 breast cancer cells
DNA are packaged into nucleosomes and chromatin. We performed incomplete MNase digestion of chromatin to identify nucleosome-free regions that may indicate active promoters and regulatory regions. Additionally, HpaII digestion was performed which cleaves CCGG sites when the internal C remains unmodi...
ORGANISM(S): Homo sapiens 
2015-02-25 | E-MTAB-1958 | biostudies-arrayexpress
ProteomicsCold Atmospheric Plasma Jet Activated Medium Promotes Wound Healing through CK2-mediated ERK and AKT signaling pathways
In this study, we aimed to explore the molecular mechanisms of wound healing affected by CAPJ using the parallel MS-based proteome and phosphoproteome. The keratinocyte, HaCaT, was used as cell mode to treat CAPJ indirectly by employing plasma activated medium (PAM) which was culture medium explored...
ORGANISM(S): Homo Sapiens (human) 
2025-02-22 | PXD050065 | JPOST Repository
TranscriptomicsRNA-seq of mRNA from MCF7 breast cancer cells and samples derived from normal breast tissues
To improve our understanding of the effect of differential methylation on gene expression between normal and tumor breast cells, we carried out RNA sequencing evaluate mRNA expression changes in normal breast tissue and MCF7 breast cancer cell line. We identified 6632 protein-coding genes to be sign...
ORGANISM(S): Homo sapiens 
2015-02-25 | E-MTAB-1961 | biostudies-arrayexpress
GenomicsGenome-wide methylome profiling of normal breast and breast tumors
To improve our understanding of the effect of differential methylation on gene expression between normal and tumor breast cells, we employed high-throughput sequencing technology to determine and compare CpG methylation of normal breast and four breast tumor genomes at single-base resolution. By com...
ORGANISM(S): Homo sapiens 
2015-02-25 | E-MTAB-2014 | biostudies-arrayexpress
TranscriptomicsProfiling DNA copy number alterations of myxofibrosarcomas with NimbleGen array CGH chips
Characterized by a wide histological spectrum, myxofibrosarcoma ranges from deceptively bland-appearing lesions to frankly pleomorphic sarcomas, representing a suitable model to elucidate the molecular aberrations in multistep disease progression. To explore cancer-associated genes of myxofibrosarco...
ORGANISM(S): Homo sapiens 
2012-02-02 | E-GEOD-35483 | biostudies-arrayexpress
TranscriptomicsMeDIP-chip from clinical cervical tissues in promoters
Utilizing methylation DNA immunoprecipitation (MeDIP) coupled with promoter tiling arrays, we analyzed the methylation profiles of pooled DNA from human cervical carcinoma and normal cervix Cervical carcinoma compaire with normal cervix
ORGANISM(S): Homo sapiens 
2012-08-05 | E-GEOD-33187 | biostudies-arrayexpress
Transcriptomics5Aza and TSA treatment of MCF7 cells (BS-seq)
The goal of this study is to identify the DNA methylation changes caused by exposure of to the DNMT inhibitor 5-aza-2’-deoxycytidine (5Aza) and HDAC inhibitor Trichostatin A (TSA). We performed whole-genome bisulfite sequencing of the drug-treated MCF7 breast cancer cell lines and compare their DN...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-MTAB-3785 | biostudies-arrayexpress
Sort   by:  
 Page size