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TranscriptomicsTranscription profiling of rat heart after ischaemia reperfusion injury and then treatment with saline, urocortin I, urocortin II or tempol
The transcriptional effects of urocortin I, urocortin II and tempol were compared to saline treatment in a rat model of in vivo coronary artery occlusion model of ischaemia/reperfusion injury of 25 min ischaemia and 2 hr reperfusion.
The treatment groups were as follows (i) sham operation or LAD...
ORGANISM(S): Rattus norvegicus 
2009-03-25 | E-MEXP-2098 | biostudies-arrayexpress
TranscriptomicsHeterochromatin-associated interactions of Drosophila HP1 with dADD1, HIPP1, and repetitive RNAs
We report chromatin-associated protein and RNA interactions of HP1a, indentified by BioTAP-XL mass spectrometry and sequencing. We identify an extensive list of both known and novel HP1a-interacting proteins from Drosophila S2 cells and from whole organisms across embryonic, larval and adult stages....
ORGANISM(S): Drosophila melanogaster 
2014-07-03 | E-GEOD-56101 | biostudies-arrayexpress
UnknownAutophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity.
Not available
S-EPMC416404 | biostudies-literature
Unknown'Mindfulness Living with Insomnia': an mHealth intervention for individuals with insomnia in China: a study protocol of a randomised controlled trial.
Not available
S-EPMC8852731 | biostudies-literature
TranscriptomicsInhibition of Respiration by Nitric Oxide Induces a Mycobacterium tuberculosis Dormancy Program
An estimated two billion persons are latently infected with Mycobacterium tuberculosis. The host factors that initiate and maintain this latent state and the mechanisms by which M. tuberculosis survives within latent lesions are compelling but unanswered questions. One such host factor may be nitric...
ORGANISM(S): Mycobacterium tuberculosis 
2007-08-21 | E-GEOD-8839 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of pig endothelium from multiple sites of coronary and non-coronary arteries
This study investigates the role of endothelial cell (EC) gene expression in the focal origin of atherosclerosis. The EC transcriptome was profiled in multiple arterial regions of normal swine. Specifically, small amounts of EC RNA were isolated from 7 athero-susceptible and 6 athero-protected regio...
ORGANISM(S): Sus scrofa 
2009-05-28 | E-CBIL-42 | biostudies-arrayexpress
MetabolomicsIntegration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes
Alteration of various metabolites has been linked to type 2 diabetes (T2D) and insulin resistance. However, identifying significant associations between metabolites and tissue-specific phenotypes requires a multi-omics approach. In a cohort of 42 subjects with different levels of glucose tolerance (...
2020-01-06 | MTBLS1051 | MetaboLights
TranscriptomicsChanges in transcription patterns in BoMac cells in response to PDD spirochetes
Papillomatous digital dermatitis (PDD) is a polymicrobial infection in soft tissue adjacent to the hoof and is the leading cause of lameness in dairy cattle. Treponema phagedenis-like (TPL) spirochetes are a constant feature of PDD lesions and are localized deep in infected tissue. Host-cell respon...
ORGANISM(S): Bos taurus 
2007-06-22 | E-GEOD-6702 | biostudies-arrayexpress
TranscriptomicsSpecification of HiPS to in vivo placental cell types
Here we identify conditions that efficiently drive specification of primed induced pluripotent stem cells to trophectoderm, named Trophoblast Stem Cell (TS). iPS-derived-TS cells share transcriptional, morphological and functional characteristics with human ex vivo cytotrophoblasts including transc...
ORGANISM(S): Homo sapiens 
2021-10-02 | E-MTAB-9526 | biostudies-arrayexpress
TranscriptomicsDifferences in platelet miRNA profiles between patients with coronary artery disease and healthy controls.
Coronary artery disease (CAD) is the leading cause of human morbidity and mortality worldwide, underscoring the need to improve diagnostic strategies. Platelets play a major role, not only in the process of acute thrombosis during plaque rupture, but also in the formation of atherosclerosis itself. ...
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-59421 | biostudies-arrayexpress
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