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We describe a novel quantitative cDNA expression profiling strategy, involving amplification of the majority of mouse transcriptome using a defined set of 44 heptamer primers. The amplification protocol allows for efficient amplification from as low as 50pg of mRNA and did not alter the expression o...
ORGANISM(S): Mus musculus 
In this study, we confirmed that transformed dedifferentiated astrocytes and neurons acquired a stem/progenitor cell state, although they still retained gene expression memory from their parental cell-type. Transcriptional network analysis on transformed cells revealed up-regulation of genes involve...
ORGANISM(S): Mus musculus 
Gupta2009 - Eicosanoid Metabolism Integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis. This model is described in the article: An integrated model of eicosanoid metabolism and signaling based ...
2024-09-02 | BIOMD0000000436 | BioModels
Transcriptomics data obtained from limiting amounts of mRNA is often noisy, providing primarily qualitative changes in transcript expressions. So far, technical variations arising out of the library preparation protocols have not been adequately characterized at reduced levels of mRNA. Here, we gene...
ORGANISM(S): Mus musculus 
Cerebral palsy is primarily an upper motor neuron disease that results in a spectrum of progressive movement disorders. Secondary to the neurological lesion, muscles from patients with cerebral palsy are often spastic and form debilitating contractures that limit range of motion and joint function....
ORGANISM(S): Homo sapiens 
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