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TranscriptomicsThe UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAs
To understand the mechanistic basis by which inositol-requiring enzyme 1 (IRE1) is involved in luminal breast cancer malignancy, we analyzed the transcriptomic signature that IRE1 regulates in breast cancer. We suppressed the activity of IRE1 RNase in luminal breast cancer SUM52 line by adenoviral-b...
ORGANISM(S): Homo sapiens 
2021-01-15 | GSE156332 | GEO
ProteomicsProbing the complementarity of FAIMS and strong cation exchange chromatography in shotgun proteomics
This dataset contains the raw data from the JASMS paper with the same title and DOI: 10.1007/s13361-012-0544-2. We compared the results of shotgun proteomic experiments of a trypsin digest of SUM52 cell lysate using 2D-LC fractionated (strong cation exchange and reversed phase of 6 SCX fractions) w...
ORGANISM(S): Homo sapiens (Human) 
2013-12-05 | PXD000596 | Pride
Cid Scx Etd Sum52 Faims 
UnknownDual HDAC/BRD4 Inhibitors Relieves Neuropathic Pain by Attenuating Inflammatory Response in Microglia After Spared Nerve Injury.
Not available
S-EPMC9606187 | biostudies-literature
GenomicsIRE1 modulates expression of a set of tumor suppressor miRNAs in luminal breast cancer cells.
To explore the regulatory mechanism by which inositol-requiring enzyme 1 (IRE1) regulates oncogenic factors, particularly RAB3B, in luminal breast cancer cells, we blocked IRE1 activity in breast cancer cell lines by using the IRE1 inhibitor 4μ8C or expressing IRE1 dominant-negative for miRNA microa...
ORGANISM(S): Homo sapiens 
2021-01-15 | GSE156331 | GEO
GenomicsThe UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAs
The UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAs
PRJNA657549 | ENA
UnknownDifferential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study.
Not available
S-EPMC7224374 | biostudies-literature
GenomicsIRE1 modulates expression of a set of tumor suppressor miRNAs in luminal breast cancer cells.
IRE1 modulates expression of a set of tumor suppressor miRNAs in luminal breast cancer cells.
PRJNA657550 | ENA
TranscriptomicsHigh FGFR2 expression is associated with reduced breast cancer risk and represses the estrogen response
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-74663 | biostudies-arrayexpress
TranscriptomicsMicroarray of A375, MDAMB468, SUM52PE, SKBR3, T47D, HCC827 and MKN45 cancer cell lines treated with rapamycin compared to DMSO-treated control
Comparison of gene expression in cancer cell lines treated with rapamycin for 24h compared to DMSO
ORGANISM(S): Homo sapiens 
2020-07-31 | E-MTAB-8727 | biostudies-arrayexpress
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