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ProteomicsHuman follicular fluid neurotransmitters LC-MSMS
Pretreated human follicular fluid was prepared for targeted metabolomics experiments. For this purpose, 12-point standard calibration curves in the respective range with reference material were measured, and the limit of detection (LOD) and limit of quantification (LOQ) for each neurotransmitter und...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031560 | Pride
Human Lc-msms Follicular fluid 
ProteomicsHuman follicular fluid hormone metabolism HPLC-MSMS
The concentrations of twenty kinds of hormones in the follicular fluid were detected by high-performance liquid chromatography–mass spectrometry (HPLC-MS/MS). An Agilent 1200 series high-performance liquid chromatography (HPLC) instrument (Agilent, USA) was utilized. A PAL autosampler (CTC, Swiss) a...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031559 | Pride
Human Hplc-msms Follicular fluid 
ProteomicsPDCD6 modulates LC3-associated phagocytosis-mediated antimicrobial defense by regulating lactate metabolism
LC3-associated phagocytosis (LAP) is critical in host defense against invading pathogens, but the molecular mechanism for LAP activation is still unclear. Here, we find programmed cell death 6 (PDCD6) as a negative regulator of LAP. PDCD6 deficiency in mice and macrophages induces enhanced bacterici...
ORGANISM(S): Homo sapiens (Human) 
2024-10-18 | PXD056047 | Pride
Lactate Lap Pdcd6 
TranscriptomicsRNA-seq of whole lungs from Irgm1-/- and wildtype littermates mice that were either uninfected or infected with influenza for 3, 6, or 10 days
We found that a dose of influenza (5,000 pfu of recombinant influenza A/WSN/33 (rWSN) H1N1 virus strain) that resulted in 50% mortality in wildtype littermate control mice showed minimal mortality in Irgm1-/- mice, indicating that Irgm1 deficiency was protective during influenza infection. This prot...
ORGANISM(S): Mus musculus 
2017-08-08 | E-MTAB-5337 | biostudies-arrayexpress
TranscriptomicsIdentifying interferon-stimulated genes enriched in multiple tissues of Irgm1-/- mice
We observed enhanced epithelial proliferation secondary to elevated Type I IFNs in multiple tissues of Irgm1-/- mice. We discovered that Type I IFNs signaled through macrophages to promote this epithelial hyperproliferation. To determine candidate factors that could play a role in this process, we p...
ORGANISM(S): Mus musculus 
2015-01-03 | E-GEOD-59603 | biostudies-arrayexpress
Proteomicsproteomic analyses of Mangifera indica L. in response to Xanthomonas critis pv. mangiferaeindicae
Mango bacterial leaf spot, which is caused by Xanthomonas critis pv. mangiferaeindicae (Xcm), poses a great threat to the development of mango planting industry.This work is the first to study the changes in gene and protein expressions in mango during Xcm infection. Our findings will provide new id...
ORGANISM(S): Mangifera Indica 
PXD043358 |
ProteomicsComprehensive 2D-LC/MS/MS profile of normal human urinary metabolome
A comprehensivemetabolomics profile of normal human urine
ORGANISM(S): Homo Sapiens 
PXD035515 |
ProteomicsAKR1B10 inhibition enhances c-Myc stability by disrupting PP2A assembly
Immunoprecipitation-MS analysis to identify AKR1B10 interacting proteins.
ORGANISM(S): Homo Sapiens 
PXD058680 |
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