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TranscriptomicsTranscription profiling of wild type fly heads (CantonS) and eye-less fly heads (sine occulis)
To identify the eye-enriched genes by comparing the mRNA expression profiles from wild type fly heads (CantonS) and eye-less fly heads (sine occulis).
ORGANISM(S): Drosophila melanogaster 
2012-05-17 | E-MEXP-49 | biostudies-arrayexpress
UnknownDiversity of Trichoderma in the unexplored Bolivian Amazon region and their potential for coffee diseases control.
Not available
S-EPMC12776340 | biostudies-literature
TranscriptomicsTranscription profiling of control and catalase-deficient Arabidopsis (Arabidopsis thaliana) plants
In plants, reactive oxygen species and, more particularly, hydrogen peroxide (H2O2) play a dual role as toxic by-products of normal cell metabolism and as regulatory molecules in stress perception and signal transduction. Peroxisomal catalases are an important sink for photorespiratory H2O2. Using A...
ORGANISM(S): Arabidopsis thaliana 
2005-10-11 | E-MEXP-449 | biostudies-arrayexpress
TranscriptomicsERalpha ChIP-chip from HeLA-ER cells treated with E2
We are studying the mechanisms by which the estrogen receptor, ERalpha, is recruited to and regulates genes with a non-direct DNA binding. We performed ChIP-chip for ERalpha in E2 treated HeLa-ER cells, and looked at 19000 RefSeq genes to determine binding patterns of the receptor at promoters. Th...
ORGANISM(S): Homo sapiens 
2011-02-22 | E-GEOD-22099 | biostudies-arrayexpress
UnknownSPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer.
Not available
S-EPMC12675285 | biostudies-literature
TranscriptomicsLncRNAs expression profiles in the livers of 20-month-old male HBx transgenic mice and C57BL/6 wild-type mice
The hepatitis B virus X protein (HBx) has been implicated as an oncogene in both epigenetic modifications and genetic regulation during hepatocarcinogenesis, but the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which regulate gene expression with little or no protein...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-42185 | biostudies-arrayexpress
TranscriptomicsQuantitative transcriptome analysis of a high-GSH producing Saccharomyces cerevisiae and the wild type based on the second generation sequencing.
The mutant Saccharomyces cerevisiae Y518 generated much more intracellular glutathione (GSH) than its counterpart dose. The RNA-seq based global transcriptome analysis was performed for exploring the potential mechanisms. Statistical analysis indicated that 1125 differentially expressed genes (fold-...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-07 | E-GEOD-47787 | biostudies-arrayexpress
TranscriptomicsEstrogen Regulates the JNK1 Genomic Localization Program in Breast Cancer Cells to Control Gene Expression and Cell Growth
JNK1 ChIP-chip and ER-alpha ChIP-chip were performed on NimbleGen genomic tiling arrays to understand the genomic binding patterns of this MAP kinase and receptor and their relationship to gene expression. ChIP-chip analysis of JNK1 occupancy at promoters before and after estrogen treatment. 2 biolo...
ORGANISM(S): Homo sapiens 
2012-03-31 | E-GEOD-13200 | biostudies-arrayexpress
TranscriptomicsIdentification and characterization of FGF2-dependent mRNA:microRNA networks during lens fiber cell differentiation
Background: FGF signaling controls numerous processes during cell lineage specification, organogenesis and terminal differentiation. In lens, FGF signaling was implicated as the key pathway that controls lens fiber cell differentiation, but little is known about its full range and spectrum of regula...
ORGANISM(S): Rattus norvegicus 
2013-09-06 | E-GEOD-50604 | biostudies-arrayexpress
GenomicsPaternally induced transgenerational inheritance of susceptibility to diabetes in mammals (MeDIP-Seq)
The global prevalence of type 2 diabetes (T2D) is increasing, and it is contributing to the susceptibility to diabetes and its related epidemic in offspring. Although the impacts of paternal T2D on metabolism of offspring have been well established, the exact molecular and mechanistic basis that med...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-43238 | biostudies-arrayexpress
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