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MetabolomicsMetabonomic analysis of human and 12 kinds of livestock mature milk

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
UnknownDown-regulated expression of microRNA-338-5p contributes to neuropathology in Alzheimer's disease.
Not available
S-EPMC6404576 | biostudies-literature
ProteomicsIllumina NovaSeq 6000 Mannose-B from Codonopsis Pilosula Modulates LAMB1 Expression to Enhance Trophoblast Function and Alleviate Subchorionic Hematoma
Introduction: This study investigates the active component Mannose-B from Codonopsis pilosula and its effect on human trophoblast cell function, particularly focusing on the regulation of Laminin Subunit Beta 1 (LAMB1) expression and its implications in subchorionic hematoma (SCH). Methods: Key gene...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD059213 | Pride
Subchorionic hematoma  codonopsis pilosula  mannose-b  laminin subunit beta 1  trophoblast cells  network pharmacology 
ProteomicsSalivary Protein Biomarker Detection of Saliva Secretion Disorder in a Primary Sjögren Syndrome Murine Model
Decreased salivary flow is one of the most common symptoms in primary Sjögren syndrome (pSS). The present study was designed to identify a salivary protein biomarker related to saliva secretion disorder in NOD/ShiLtJ mice, a pSS primary murine model. The stimulated saliva was collected from NOD/ShiL...
ORGANISM(S): Mus musculus (Mouse) 
2018-03-21 | PXD008199 | Pride
Biomarker  saliva secretion disorder  sjögren syndrome  saliva  differential proteomic analysis 
UnknownAstral-based DIA proteomics analysis reveals the effects of selenium on Pleurotus pulmonarius.
Not available
S-EPMC12297576 | biostudies-literature
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
ProteomicsAstral-based DIA proteomics analysis reveals the effects of selenium on Pleurotus pulmonarius
his study investigates the effects of sodium selenite on the yield, selenium content, and proteomic profile of Pleurotus pulmonarius (P. pulmonarius). Treatment with 2 μg/mL sodium selenite (PP-Se2) resulted in a 17.87% increase in the yield of P. pulmonarius. In contrast, treatment with 10 μg/mL so...
ORGANISM(S): Pleurotus pulmonarius 
2025-07-22 | PXD065347 | Pride
Pleurotus pulmonarius  sodium selenite  proteomics  selenium stress 
UnknownACE2 inhibits breast cancer angiogenesis via suppressing the VEGFa/VEGFR2/ERK pathway.
Not available
S-EPMC6482513 | biostudies-literature
UnknownProteomics Analysis to Explore the Resistance Genes of Silkworm to Bombyx mori Nuclear Polyhedrosis Virus.
Not available
S-EPMC10815149 | biostudies-literature
ProteomicsProteomic analyses reveal the key role of gene co-option in the evolution of Scaly-foot Snail scleritome
This project aims to uncover the co-option and preservation of ancient proteins through the process of sclerite development in deep-sea creature Chrysomallon Squamiferum. Proteomes of the evolutionarily novel hard part, the sclerite and the long conserved spirial shell were studied, in comparison to...
ORGANISM(S): Chrysomallon squamiferum Gigantopelta aegis 
2025-05-06 | PXD051659 | Pride
Shell Chrysomallon Gigantopelta Biomineralization Proteome Sclerite 
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