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Proteomicsproteomics analysis of small extracellular vesicles from mouse liver tissue across age groups
The project aims to investigate the proteomic changes in small extracellular vesicles (sEVs) derived from mouse liver tissue across different age groups to identify proteins associated with aging. The study employs a comprehensive proteomic analysis to reveal age-dependent alterations in protein exp...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-09 | PXD059350 | Pride
Mouse liver sevs lc-ms/ms aging 
ProteomicsProtective mechanisms of heparin against AGEs-induced endothelial injury
Advanced glycation end products (AGEs) in diabetes can cause endothelial damage. Heparin, widely known as a recognized anticoagulant, is also a multifunctional therapeutic drug. This study investigated whether heparin could ameliorate AGEs-induced endothelial injury. Remarkably, heparin effectively ...
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD056219 |
ProteomicsPinctada fucata martensii shell matrix protein LC-MSMS
Nacre, the iridescent material found in pearls and shells of molluscs, is formed through an extraordinary process of matrix-assisted biomineralization. Despite recent advances, many parts of the biomineralization process and its evolutionary origin remain a mystery. The pearl oyster Pinctada fucata ...
ORGANISM(S): Bivalvia 
2017-07-07 | PXD006786 | Pride
Lc-msms Shell matrix protein Pearl oyster 
UnknownAutophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA.
Not available
S-EPMC9532426 | biostudies-literature
UnknownDeep segmentation networks predict survival of non-small cell lung cancer.
Not available
S-EPMC6872742 | biostudies-literature
MetabolomicsVGLL4 modulates Paneth cells and sustains intestinal homeostasis.
Paneth cells are defensive cells in the intestinal tract, which secrete niche factors and antimicrobial peptides (AMPs) to maintain the small intestinal stem cell niche and immune homeostasis. Here, we show that Vestigial-like family member 4 (VGLL4) plays a pivotal role in maintaining small intesti...
2026-03-12 | MTBLS10456 | MetaboLights
ProteomicsLabel-free quantitative proteomics for screening dynamic autophagy-related proteins during nutrient deprivation in MEFs
A Label-free quantitative proteomic profiling was performed on MEFs with or without nutrient starvation.
ORGANISM(S): Mus Musculus 
PXD025450 |
TranscriptomicsTranscriptome sequencing of naked mole rat, Heterocephalus glaber
Deep sequencing of mRNA from naked mole rat Analysis of ploy(A)+ RNA of different specimens: brain, kidney, liver from new born , 4 years old , 20 years old and 4 years old hypoxia-exposed naked mole rat
ORGANISM(S): Heterocephalus glaber 
2011-10-12 | E-GEOD-30337 | biostudies-arrayexpress
ProteomicsProteotypic differences of follicular-patterned thyroid neoplasms
The diagnosis of follicular-patterned thyroid tumors such as follicular adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by prote...
ORGANISM(S): Homo Sapiens 
PXD036553 |
ProteomicsComputational Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage and Applications to 15 Tumors
a computational strategy for the size optimization of DIA spectral library, which refines a comprehensive library by a prior analysis of DIA data of a particular tissue type
ORGANISM(S): Homo Sapiens 
2021-12-27 | PXD030648 |
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