Sort   by:  
 Page size 
MetabolomicsShort-Term Clinical Response and Changes in the Fecal Microbiota and Metabolite Levels in Patients with Crohn's Disease After Stem Cell Infusions
Recent studies have shown a close relationship between the gut microbiota and Crohn's disease (CD). This study aimed to determine whether mesenchymal stem cell (MSC) treatment alters the gut microbiota and fecal metabolite pathways and to establish the relationship between the gut microbiota and fec...
2025-07-03 | MTBLS6288 | MetaboLights
TranscriptomicsExpression data from adult wistar female rat 5mm spinal cord tissue
We used microarray gene expression analyses to unveil the mechanisms underlying NT-3-chitosan-induced spinal cord regeneration. Complete transaction of thoracic spinal cord at T7/8 was performed, with a 5 mm segment of the spinal cord being removed. The emptied space where either refilled with a 5mm...
ORGANISM(S): Rattus norvegicus 
2015-11-02 | E-GEOD-69334 | biostudies-arrayexpress
ProteomicsSubcellular Interactomes Revealed by Merging APEX with Cross-linking Mass Spectrometry
An integrating APEX proximity labeling and chemical cross-linking coupled with mass spectrometry (CXMS) platform named APEX-CXMS for spatially resolved subcellular interactome profiling in a high-throughput ma
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD033838 |
ProteomicsExploration of the antioxidant effect of spermidine on the ovary and screening and identification of differentially expressed proteins
Spermidine is a naturally occurring polyamine compound that has many biological functions, such as inducing autophagy and anti-inflammatory and anti-aging effects. In this study, ICR mice were fed exogenous spermidine drinking water for three months to explore the regulation of ovarian function by s...
ORGANISM(S): Mus Musculus 
2022-12-12 | PXD038755 |
ProteomicsConformational dynamics of the activated GLP-1 receptor-Gs complex revealed by cross-linking mass spectrometry and integrative modeling
Despite revolutionary advancements in GPCR structural biology, our understanding of the complexity of GPCR activation and signaling would not be complete without complementary information on the conformational dynamics. Yet it is particularly challenging to study the dynamics of GPCR complexes with ...
ORGANISM(S): Homo Sapiens 
2023-01-08 | PXD039315 |
ProteomicsImproving Mass Spectrometry Analysis of Protein Structures with Arginine-Selective Chemical Cross-linkers
we develop a series of arginine selective bifunctional aromatic glyoxal cross-linkers (ArGOs) and demonstrate their ability to cross-link model proteins and a protein complex. We also introduce the first arginine-lysine heterobifunctional cross-linker (KArGO), which provides significantly greater su...
ORGANISM(S): Escherichia Coli 
2019-01-14 | PXD012341 |
ProteomicsProteomic analysis of Hypsibius henanensis sp.nov. suffered from 12C6+ heavy ion radiation based on label-free technology
Tardigrades are a kind of species that can tolerate ultra-high doses of ionizing radiation. Here, we used heavy ions at different doses of 0,200 and 2000Gy to irradiate Hypsibius henanensis sp.nov.. Label-free proteomic identification was performed on the samples, each dose containing 3 repetitions
ORGANISM(S): Tardigrada 
2023-09-20 | PXD045537 |
ProteomicsDetection of betalains from the extracts of H. henanensis sp. nov.
Identification of betalains from the extracts of H. henanensis sp. nov. using untargeted metabolomics.
ORGANISM(S): Tardigrada 
2024-03-22 | PXD050882 |
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD055730 |
TranscriptomicsCritical Role of Sphingolipid Pathway Components in Murine Radiation-Induced Lung Injury: Protection by Sphingosine-1-Phosphate Analogues
Clinically significant radiation-induced lung injury (RILI) is associated with significant morbidity and mortality and a common toxicity in patients administered thoracic radiotherapy. While the molecular etiology of RILI is poorly understood, we previously characterized a murine model of RILI in wh...
ORGANISM(S): Mus musculus 
2010-11-17 | E-GEOD-25295 | biostudies-arrayexpress
Sort   by:  
 Page size