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TranscriptomicsTranscription profiling of human stage non-small cell lung cancer samples, metaanalysis for a predictive signature
We applied a meta-analysis of datasets from seven different microarray studies on lung cancer for differentially expressed genes related to survival time (under 2 y and over 5 y). Systematic bias adjustment in the datasets was performed by distance-weighted discrimination (DWD). We identified a gene...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6253 | biostudies-arrayexpress
TranscriptomicsOptimizing molecular signatures for prostate cancer recurrence
The derivation of molecular signatures indicative of disease status and predictive of subsequent behavior could facilitate the optimal choice of treatment for prostate cancer patients. In this study, we conducted a computational analysis of gene expression profile data obtained from 79 cases, 39 of ...
ORGANISM(S): Homo sapiens 
2010-11-05 | E-GEOD-25136 | biostudies-arrayexpress
TranscriptomicsMolecular Biomarker Signature for Bladder Cancer Detection
In this study we applied differential gene expression analysis to exfoliated human urothelia obtained from patients of known bladder disease status. Selected targets from the microarray data were validated in an independent set of samples using a quantitative PCR approach. Total RNA was extracted fr...
ORGANISM(S): Homo sapiens 
2013-01-08 | E-GEOD-31189 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of bovine in vivo pre-implantation development
During mammalian pre-implantation embryonic development dramatic and orchestrated changes occur in gene transcription. The identification of the complete changes has not been possible until the development of the Next Generation Sequencing Technology. Here we report the first transcriptome dynamics...
ORGANISM(S): Bos taurus 
2014-09-10 | E-GEOD-59186 | biostudies-arrayexpress
ProteomicsProteomic analysis of patient tissue reveals parallels and discrepancies in immune and mitochondrial processes across mouse models of motor neurone disease
Motor neurone disease (MND) is a fatal neurodegenerative disease resulting in the progressive loss of motor neurons in the brain and spine. More than 95% of cases are pathologically characterized by the cytoplasmic accumulation of hyperphosphorylated and ubiquitinated transactive response DNA-bindin...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-10-06 | PXD062542 | Pride
Motor neurone disease  amyotrophic lateral sclerosis  immune-mediated pathology  mitochondrial dysfunction  neurodegeneration  tdp-43  tmt-proteomics. 
ProteomicsIdentification of ATG7 as a protein ATG8ylation substrate
Identification of endogenous protein ATG8ylated ATG7 over 100kDa fractions by MS
ORGANISM(S): Homo Sapiens 
2025-06-29 | PXD065606 |
ProteomicsKAT8-TurboID labelling proteins
V5-TurboID-KAT8-expressing A375 stable cells were treated with biotin and then underwent streptavidin purification and mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-12-05 | PXD038565 |
ProteomicsIRF1 acetylation sites by KAT8
Aim to identify the IRF1 acetylation site by KAT8 in cotransfected HEK293T cells
ORGANISM(S): Homo Sapiens 
2022-12-05 | PXD038568 |
ProteomicsComparison of cerebrospinal fluid proteomics between Demyelinating disease and non-inflammatory neurological controls
Demyelinating disease is a disease of the nervous system in which the nerve demyelinating is the main or primary lesion, and the axon, cell body and glia are relatively lightly damaged. It can occur in the central nervous system or the peripheral nervous system. The demyelinating diseases of central...
ORGANISM(S): Homo Sapiens 
2020-12-09 | PXD023027 |
ProteomicsUrine proteomics in primary antiphospholipid syndrome
In this study, using proteomics study of urine samples from patients with primary APS (PAPS) and healthy controls (HC), we identified several proteins that discriminated Obstetric APS (OAPS) and Thrombotic APS (TAPS) from each other, as well as from HC.
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027694 |
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