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TranscriptomicsTranscription profiling of human blood from kidney transplant patients to identify biomarkers for early and late stage chronic allograft nephropathy by genomic profiling
Despite significant improvements in life expectancy of kidney transplant patients due to advances in surgery and immunosuppression, Chronic Allograft Nephropathy (CAN) remains a daunting problem. A complex network of cellular mechanisms in both graft and peripheral immune compartments complicates th...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-12187 | biostudies-arrayexpress
TranscriptomicsGene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms that Correlate with Worse Long-term Outcomes
Rationale: Interstitial fibrosis and tubular atrophy (IFTA) is found in ~25% of 1-year biopsies post-transplant(1, 2). It correlates with decreased graft survival when histological evidence of inflammation is present¬.(3-5) Identifying the etiology of IFTA is important because longterm graft surviva...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-76882 | biostudies-arrayexpress
UnknownBis{4-[(Z)-N'-(4-hydroxy-benzyl-idene)hydrazino]-8-(trifluoro-meth-yl)quinolinium} sulfate dihydrate.
Not available
S-EPMC2960448 | biostudies-literature
TranscriptomicsGENOMICS TO IDENTIFY HLA IDENTICAL RENAL TRANSPLANT TOLERANCE SIGNATURES
Immunosuppression is needed in HLA identical sibling renal transplantation. We conducted a tolerance trial in this patient cohort using Alemtuzumab induction, donor hematopoietic stem cells, tacrolimus/mycophenolate immunosuppression converted to sirolimus, planning complete drug withdrawal by 24 m...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-45593 | biostudies-arrayexpress
ProteomicsGlobal proteomics of Aedes albopictus (U4.4) cells upon chikungunya virus infection
In this work, we studied the impact of chikungunya virus (CHIKV) on the global proteome of functionally Dicer 2 active Aedes albopictus cells i.e. U4.4 cells at 12 hours post infection (hpi) and 60 hpi using mass spectrometry analysis. The non-radio labelling quantitative proteomics analysis of unin...
ORGANISM(S): Aedes albopictus 
2022-11-18 | PXD033252 | Pride
Proteomics U4.4 cells Mass spectrometry Chikunugunya Aedes albopictus 
ProteomicsGlobal proteome characterization of a three-dimensional human chondrocyte cell culture system during chikungunya virus (CHIKV) infection reveals distinct immune and inflammatory signatures
Chikungunya virus (CHIKV) belongs to alphavirus infections which often tend to deliberate musculoskeletal disorders affecting joints, muscles, and bones. Primary cells isolated from patients undergoing total knee replacement were utilized to perceive the effect of virus infection on it, upon isolati...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD055872 | Pride
2-dimension (2d) monolayer Chondrocytes Chikungunya virus (chikv) Proteomics 3-dimension (3d) spheroid cell culture 
UnknownActivation of an atypical plant NLR with an N-terminal deletion initiates cell death at the vacuole.
Not available
S-EPMC11467418 | biostudies-literature
UnknownInvestigation of a severe SARS-CoV-2 outbreak in a long-term care home early in the pandemic.
Not available
S-EPMC8158000 | biostudies-literature
UnknownSignaling sickness: the role of recalled sickness behavior and psychosocial factors in shaping communication style.
Not available
S-EPMC8364984 | biostudies-literature
UnknownSynthesis, spectroscopic and crystal structure studies of N-{3-cyano-1-[2,6-di-chloro-4-(tri-fluoro-meth-yl)phen-yl]-4-(ethyl-sulfan-yl)-1H-pyrazol-5-yl}-2,2,2-tri-fluoro-acetamide.
Not available
S-EPMC9638981 | biostudies-literature
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