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ProteomicsGID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
How are E3 ubiquitin ligases configured to match substrate quaternary structures? Here, by studying the yeast GID complex, mutation of which is Glucose-Induced Degradation deficient, we discover supramolecular chelate assembly as an E3 ligase strategy for targeting an oligomeric substrate. Cryo EM s...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-04-28 | PXD024462 | Pride
Supramolecular assembly Metabolism Gluconeogenesis Cryo em E3 ligase Gid Ubiquitin Ctlh 
UnknownBiomimetic temporal self-assembly via fuel-driven controlled supramolecular polymerization.
Not available
S-EPMC5878180 | biostudies-literature
UnknownSupramolecular Self-Assembly of Engineered Polyproline Helices.
Not available
S-EPMC10357564 | biostudies-literature
UnknownThiosquaramide-Based Supramolecular Polymers: Aromaticity Gain in a Switched Mode of Self-Assembly.
Not available
S-EPMC7705886 | biostudies-literature
ProteomicsDegron mimicry modulates selective substrate recruitment by CTLH E3 supramolecular assembly
Selective protein degradation by the Ubiquitin Proteasome System (UPS) is largely regulated by multi-subunit E3 ligase complexes commonly utilizing interchangeable degron-receptors to target a plethora of different substrates. Here, we identified nicotinamide/nicotinacid-mononlucletide-adenylyltrans...
ORGANISM(S): Homo sapiens (Human) 
2024-05-16 | PXD044126 | Pride
Proteomics 
UnknownExposing Mechanisms for Defect Clearance in Supramolecular Self-Assembly: Palladium-Pyridine Coordination Revisited.
Not available
S-EPMC10091417 | biostudies-literature
UnknownA study on the self-assembly mode and supramolecular framework of complexes of cucurbit[6]urils and 1-(4-methoxyphenyl)piperazine.
Not available
S-EPMC9057125 | biostudies-literature
UnknownIntra- and intermolecular self-assembly of a 20-nm-wide supramolecular hexagonal grid.
Not available
S-EPMC7375338 | biostudies-literature
UnknownUnderstanding Supramolecular Assembly of Supercharged Proteins.
Not available
S-EPMC9523778 | biostudies-literature
UnknownSelf-Assembly of Supramolecular Fractals from Generation 1 to 5.
Not available
S-EPMC6348470 | biostudies-literature
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