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TranscriptomicsSSH-PCR dehydrated supraoptic nucleus
The magnocellullar neurons (MCNs) of the supraoptic nucleus (SON) of the hypothalamus are the principle source of the neuropeptide hormone vasopressin (VP), which has a crucial role in osmoregulation. Physiological activation of the SON by dehydration results is a massive release of VP from stores i...
ORGANISM(S): Rattus norvegicus 
2010-06-30 | E-GEOD-3132 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the osmotic and reproductive remodelling of the female rat supraoptic nucleus
The supraoptic nucleus (SON) of the hypothalamus is an important integrative brain structure that co-ordinates responses to perturbations in water balance and regulates maternal physiology through the release of the neuropeptide hormones vasopressin and oxytocin into the circulation. Both dehydratio...
ORGANISM(S): Rattus norvegicus 
2011-12-29 | E-GEOD-30733 | biostudies-arrayexpress
TranscriptomicsNIA Neuroarray dehydration
The magnocellular neurons (MCNs) of the supraoptic nucleus (SON) and paraventricular nucleus (PVN) of the hypothalamus are the principal site of biosynthesis of prepropeptide precursor of the antidiuretic hormone vasopressin (VP). This precursor is processed during anterograde axonal transportation ...
ORGANISM(S): Rattus norvegicus 
2010-06-30 | E-GEOD-3133 | biostudies-arrayexpress
TranscriptomicsA comparison of physiological and transcriptome responses to water deprivation and salt loading in the rat supraoptic nucleus
Salt loading (SL) and water deprivation (WD) are experimental challenges that are often used to study the osmotic circuitry of the brain. Central to this circuit is the supraoptic nucleus (SON) of the hypothalamus, which is responsible for the biosynthesis of the hormones, vasopressin (AVP) and oxyt...
ORGANISM(S): Rattus norvegicus 
2015-02-05 | E-GEOD-65663 | biostudies-arrayexpress
ProteomicsPeptidomics analysis of dromedary camel supraoptic nucleus by tandem mass spectrometry
Peptides were qualitatively characterized in supraoptic nuclei (SON)of dromedary camels by liquid chromatography-mass spectrometry/mass spectrometry. Samples collected in winter and summer were analyzed separately. Qualitative seasonal differences were noted. The presence of the PMCH hormone by dete...
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2019-11-11 | PXD013869 | Pride
Peptidomics Dehydration Supraoptic nucleus (son) 
GenomicsAge-dependent transcriptome characterization of the rat supraoptic nucleus (RNA-Seq)
Age-dependent transcriptome characterization of the rat supraoptic nucleus (RNA-Seq)
PRJNA967014 | ENA
GenomicsAge-dependent DNA methylation characterization of the rat supraoptic nucleus (Methylation)
Age-dependent DNA methylation characterization of the rat supraoptic nucleus (Methylation)
PRJNA967023 | ENA
TranscriptomicsTranscription profiling of rat hypothalamo-neurohypophyseal system reveals gene expression is highly strain-dependant
We have used microarrays to comprehensively describe the transcriptomes of the supraoptic nucleus (SON), the paraventricular nucleus (PVN) and the neurointermediate lobe (NIL) of adult male Sprague-Dawley (SD) and Wistar-Kyoto (WKY) rats, as well as the paraventricular nucleus of Wistar (WIST) rats....
ORGANISM(S): Rattus norvegicus 
2008-10-25 | E-GEOD-8491 | biostudies-arrayexpress
ProteomicsGeneral anaesthesia leads to phosphoproteome changes in proteins involved in cytoskeleton remodelling and synaptic processes in the supraoptic nucleus of the hypothalamus
Despite the widespread use of general anaesthetics, the mechanisms mediating their effects are still not understood. Although suppressed in most parts of the brain, neuronal activity, as measured by FOS activation, is increased in the hypothalamic supraoptic nucleus (SON) by numerous general anaesth...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-23 | PXD039391 | Pride
Synapse Cytoskeleton Anaesthetic Phosphorylation Rat Supraoptic Lc-msms 
Methylation profilingAge-dependent DNA methylation characterization of the rat supraoptic nucleus (Methylation)
Our prior studies indicat age-dependent contralateral axonal sprouting following unilateral lesion of magnocellular neurons in the supraoptic nucleus. We performed Oxford Nanopore sequencing of the rat supraoptic nucleus to determine changes in DNA methylation with age.
ORGANISM(S): Rattus norvegicus 
2023-08-16 | GSE231615 | GEO
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