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Oxygen minimum zones (OMZs) are expanding due to increased sea surface temperatures, subsequent increased oxygen demand through respiration, reduced oxygen solubility, and thermal stratification driven in part by anthropogenic climate change. Devil's Hole, Bermuda is a model ecosystem to study OMZ m...
2024-02-27 | MTBLS8122 | MetaboLights
In aquatic environments, the production and consumption of organic compounds is directly tied to the metabolic potential of the in situ microbial community. The community’s metabolic potential can be assessed using metatranscriptomics, which is a measure of gene expression in the environment. More r...
2016-01-14 | MTBLS293 | MetaboLights
The interactions of nanoparticles (NPs) with macrophages after intravenous injection are critical in determining their biodistribution and pharmacokinetics. The formation of protein corona (PC) on the nanoparticles, often a result of NP-plasma protein interactions, influences macrophage response, th...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD051722 | Pride
The cell surface proteome is dynamic and has fundamental roles in cell signaling. Many surface membrane proteins are proteolytically released into a cell’s secretome, where they can have additional functions in cell-cell-communication. Yet, it remains challenging to determine the surface proteome an...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-08 | PXD008619 | Pride
Gold nanoparticles (Au NPs) are uniquely suited for various biomedical applications due to the combination of their optical properties with their easily functionalized surfaces. The Au NP surface can be tailored to improve biocompatibility while also attaching targeting ligands or drugs. However, in...
ORGANISM(S): Homo sapiens 
Understanding the interfacial structure between nanomaterials and lipoproteins is crucial for gaining profound insights into how nanomaterials impact lipoprotein structure and interfere with lipid metabolism. In this study, we employed graphene oxide (GO) nanosheets (NSs) with precisely controlled s...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044475 | Pride
Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in HepG2 Cells
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