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ProteomicsThe secreted proteases Aur, ScpA, SspA and SspB suppress virulence of Staphylococcus aureus USA300 by shaping the extracellular proteome
Surface-located and secreted virulence factors of the Gram-positive bacterial pathogen Staphylococcus aureus are key drivers for infection of the human host. Proteolytic enzymes may contribute to virulence by breaking primary barriers and host immune defenses. Therefore, the objective of our present...
ORGANISM(S): Staphylococcus aureus 
2025-04-22 | PXD056653 | Pride
Staphylococcus aureus  virulence  proteases  peptidoglycan hydrolase  cell lysis 
UnknownSurfaceome and exoproteome of a clinical sequence type 398 methicillin resistant Staphylococcus aureus strain.
Not available
S-EPMC5668672 | biostudies-literature
ProteomicsSurfacome analysis of Lactobacillus rhamnosus GG and Lactobacillus rhamnosus Lc705
The present study reports comparative surfacomics (study of cell-surface exposed proteins) of the probiotic Lactobacillus rhamnosus strain GG and the dairy strain Lc705.
ORGANISM(S): Lactobacillus 
2016-07-01 | PXD001201 | Pride
Cell-surface bound proteins L. rhamnosus gg and l. rhamnosus lc705 Lc-ms/ms 
ProteomicsTryptic striptease of Staphylococcus aureus unveils the cell surface localization of immunodominant epitopes
The opportunistic pathogen Staphylococcus aureus has become a major threat for human health and well-being by developing resistance to antibiotics, and by its fast evolution into new lineages that rapidly spread within the healthy human population. This calls for the development of active or passive...
ORGANISM(S): Staphylococcus aureus (strain Newman) Staphylococcus aureus (strain USA300) 
2020-06-18 | PXD000156 | Pride
Cellwall Surfacome Exoproteome Staphylococcus aureus Virulence factor 
ProteomicsWithin-host adaptive phenotypic responses of bovine Staphylococcus aureus
The Gram-positive bacterium S. aureus is one of the most common causes of contagious bovine mastitis. A predominant S. aureus clone persists within its host over a long period. In the present study, we compared the surface proteome of two isolates, collected from a naturally infected dairy cow with ...
ORGANISM(S): Staphylococcus aureus 
2021-08-14 | PXD025013 | Pride
Chronic bovine mastitis Surface shaving Biotinylaton Host adaption Staphylococcus aureus Cell surface proteome 
ProteomicsExoproteomes of S. aureus spa type t437 isolates
A total of 20 S. aureus spa type t437 isolates were used for exoproteome analyses in the present study. Ten of them were selected from MLVA type (MT) 621 group which has was shown to represent the most predominant class of S. aureus isolates with the spa type t437; the other ten isolates belonged to...
ORGANISM(S): Staphylococcus aureus 
2019-05-24 | PXD009082 | Pride
Staphylococcus aureus 
ProteomicsComparative exoproteome and virulence analysis of different clusters of Staphylococcus aureus with the Sequence Type ST398
Livestock-associated (LA) methicillin-resistant Staphylococcus aureus (MRSA) and strains of sequence type 398 (ST398), which first became known for its widespread colonization of pigs but are now also rapidly emerging in the number of human colonization and infections. The ability of broad host adap...
ORGANISM(S): Staphylococcus aureus 
2020-08-05 | PXD013951 | Pride
Virulence Methicillin-resistant staphylococcus aureus (mrsa) Mobile genetic elements (mge) Extracellular proteome Label-free quantitative mass spectrometry 
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