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TranscriptomicsAssessing concordance of drug-induced transcriptional response in rodent liver and cultured hepatocytes
The effect of drugs, disease and other perturbations on mRNA levels are studied using gene expression microarrays or RNA-seq, with the goal of understanding molecular effects arising from the perturbation. Previous comparisons of reproducibility across laboratories have been limited in scale and fo...
ORGANISM(S): Rattus norvegicus 
2015-11-12 | E-GEOD-74903 | biostudies-arrayexpress
MetabolomicsTemporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment
Lung cancer causes more deaths in men and women than any other cancer related disease. Currently, few effective strategies exist to predict how patients will respond to treatment. We evaluated the serum metabolomic profiles of 25 lung cancer patients undergoing chemotherapy ± radiation to evaluate t...
2017-01-19 | MTBLS200 | MetaboLights
TranscriptomicsDevelopment and Validation of a Novel Molecular Biomarker Diagnostic Test for the Early Detection of Sepsis
Introduction: Sepsis is a complex immunological response to infection characterized by early hyperinflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on ...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28750 | biostudies-arrayexpress
GenomicsEpigenomic profiling of Non-small-cell Lung Cancer (NSCLC) cells with or without Eed
Polycomb repressive complexes (PRC) are frequently implicated in human cancer acting either as oncogenes or tumor suppressors. Here we show that PRC2 is a critical regulator of Kras-driven non-small-cell lung cancer (NSCLC) progression. Modulation of PRC2 by either Ezh2 overexpression or Eed deletio...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-61190 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of multiple human tumour specimens of different anatomical origin arrayed against a common reference
Multiple tumour specimens of different anatomical origin arrayed against a common reference.
ORGANISM(S): Homo sapiens 
2005-09-20 | E-MEXP-113 | biostudies-arrayexpress
UnknownIsl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.
Not available
S-EPMC5685895 | biostudies-literature
UnknownPredictors of nicotine dependence among adolescent waterpipe and cigarette smokers: A 6-year longitudinal analysis.
Not available
S-EPMC7861130 | biostudies-literature
UnknownThe impact of social determinants of health on outcomes of brexucabtagene autoleucel in adults with relapsed/refractory B-cell acute lymphoblastic leukemia.
Not available
S-EPMC12583187 | biostudies-literature
UnknownAcculturative Orientations Among Hispanic/Latinx Caregivers in the ABCD Study: Associations With Caregiver and Youth Mental Health and Youth Brain Function.
Not available
S-EPMC10593892 | biostudies-literature
UnknownPriority Questions and Horizon Scanning for Conservation: A Comparative Study.
Not available
S-EPMC4729468 | biostudies-literature
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