Sort   by:  
 Page size 
ProteomicsRGS10L phosphorylation site determination Top-Down
The phosphorylation sites of 4 recombinant RGS10L variants were determined using Top-Down study.
ORGANISM(S): Mus musculus (Mouse) Escherichia coli 
2021-11-03 | PXD023752 | Pride
Rgs10l Phoshorylation Top-down 
ProteomicsRGS10L phosphorylation site determination Bottom-Up
RGS10L phosphorylatin site was determined. Trypsin is not good for generating a peptide containing the potential site, and the initial study was done using the intact protein. From the Top-Down study, the phosphorylatin site of the A->S variant was ambiguous. The firnal confirmation was done usin...
ORGANISM(S): Mus musculus (Mouse) Escherichia coli 
2021-11-03 | PXD023753 | Pride
Rgs10l Bottom-up Phosphorylation 
ProteomicsBehavioral Manipulation of Ixodes scapularis by Ehrlichia muris eauclairensis: Implications for Tick-Borne Disease Transmission
To understand how EME influence tick behavior, we analyzed the tick nervous system; testing for the presence of EME in the synganglion, then performing proteomic studies on the synganglion during resting, and attachment/feeding phases.
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) Ehrlichia muris Mus musculus (Mouse) 
2025-05-21 | PXD060563 | Pride
Ixodes scapularis Synganglion Eme Dia Ehrlichia muris eauclarensis Lfq Tick Nymph Ehrlichia 
ProteomicsMosquito salivary apyrase regulates blood meal hemostasis and drives malaria parasite transmission
To identify the putative salivary tPA activator, we fractionated salivary proteins by size-exclusion chromatography and identified fraction Z8 as the strongest tPA activator, whereas the adjacent fractions Z7 and Z9 activated tPA at lower levels. Mass spectrometry analysis of these fractions identif...
ORGANISM(S): Anopheles gambiae (African malaria mosquito) 
2025-01-16 | PXD052155 | Pride
Mosquito Salivary glands Anopheles gambiae Size-exclusion chromatography 
TranscriptomicsMYBPH, a novel transcriptional target of NKX2-1/TTF-1, inhibits ROCK1 and actomyosin assembly, and reduces cell motility and tumor metastasis
Cell migration driven by actomyosin filament assembly is a critical step in tumour invasion and metastasis. Herein, we report identification of myosin binding protein H (MYBPH) as a transcriptional target of NKX2-1 (also known as TTF-1 and TITF1), a lineage-survival oncogene in lung adenocarcinoma. ...
ORGANISM(S): Homo sapiens 
2011-12-22 | E-GEOD-26721 | biostudies-arrayexpress
TranscriptomicsTTF-1-induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma
Adenocarcinoma is the most common histologic subtype of lung cancer, which is the leading cause of cancer death. We and others previously identified TTF-1, a lineage-specific transcription factor required for branching morphogenesis and physiological lung functions, as a lineage-survival oncogene in...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-25830 | biostudies-arrayexpress
Sort   by:  
 Page size