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TranscriptomicsMolecular Profiling of Chemoresistant Slow Cycling Cancer-Initiating Cells from human colorectal cancer, glioma and melanoma.
SUMMARY: Dormant or slow cycling tumour cells can form a residual chemoresistant reservoir responsible for relapse in patients, years after curative surgery and adjuvant therapy. Since their isolation from human tumors has been a long-stalled technical challenge preventing a direct study of their fu...
ORGANISM(S): Homo sapiens 
2018-06-28 | E-MTAB-4004 | biostudies-arrayexpress
TranscriptomicsDPPA3-HIF1a axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype (DNA methylation arrays)
Tumor relapse is linked to rapid chemoresistance and represents a bottleneck for cancer therapy success. Engagement of a reduced proliferation state is a non-mutational mechanism exploited by cancer cells to bypass therapy-induced cell death. Through combining pulse-chase experiments in engineered C...
ORGANISM(S): Homo sapiens 
2023-07-30 | E-MTAB-12892 | biostudies-arrayexpress
TranscriptomicsDPPA3-HIF1a axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
Comparative transcriptome of SW1222 colorectal cancer (CRC) cells that overexpress or are depleted of DPPA3 to identify genes involved in regulating of the slow-cycling cancer cell properties to uncover the molecular mechanism of the non-mutational chemoresistant phenotype.
ORGANISM(S): Homo sapiens 
2023-08-02 | GSE207862 | GEO
UnknownCancer stem cells from colorectal cancer-derived cell lines.
Not available
S-EPMC2840416 | biostudies-literature
UnknownAn in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate.
Not available
S-EPMC4294113 | biostudies-literature
UnknownLongitudinal Photoacoustic Imaging of the Pharmacodynamic Effect of Vascular Targeted Therapy on Tumors.
Not available
S-EPMC7611302 | biostudies-literature
UnknownThree-dimensional analysis of tumour vascular corrosion casts using stereoimaging and micro-computed tomography.
Not available
S-EPMC4398341 | biostudies-literature
UnknownA pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry.
Not available
S-EPMC4151562 | biostudies-literature
GenomicsDPPA3-HIF1a axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
DPPA3-HIF1a axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
PRJNA857451 | ENA
UnknownComparison of targeting two antigens (GPA33 versus HER2) for <sup>225</sup>Ac-pretargeted alpha-radioimmunotherapy of colorectal cancer.
Not available
S-EPMC12315807 | biostudies-literature
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