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UnknownCross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes.
Not available
S-EPMC7870876 | biostudies-literature
MetabolomicsIntegrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non-functioning pituitary adenomas

Pituitary adenomas constitute 10 to 25% of intracranial tumors, rendering them one of the most prevalent types of brain tumors. While the majority of pituitary adenomas are benign, ~35% exhibit invasive behavior. Compared with their non-invasive counterparts, invasive pituitary adenomas are more ...

2025-12-09 | MTBLS13478 | MetaboLights
GenomicsAn iPSC-derived neuronal model of DNAJC6 parkinsonism reveals neurodevelopmental and synaptic vesicle recycling defects
An iPSC-derived neuronal model of DNAJC6 parkinsonism reveals neurodevelopmental and synaptic vesicle recycling defects
PRJNA859666 | ENA
TranscriptomicsSystem-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms
Detailed analysis of disease-affected tissue provides insight into molecular mechanisms contributing to pathogenesis. Substantia nigra, striatum and cortex are functionally connected with increasing degrees of alpha-synuclein pathology in Parkinson's disease. Functional and causal pathway analysis o...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-54282 | biostudies-arrayexpress
UnknownEvaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer's disease continuum.
Not available
S-EPMC10612328 | biostudies-literature
ProteomicsEstradiol replacement modulates synaptic transmission-related proteins in the hippocampus of ovariectomized rats: an exploratory proteomic approach
Background: The loss of ovarian-derived hormones that characterizes postmenopause influences cognition, emotion and energy homeostasis, processes integrated by the hippocampus. The cellular and molecular mechanisms by which estradiol influences this brain system have not been fully understood. The p...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-14 | PXD040816 | Pride
Synapse Postmenopause Glutamatergic synapse Mitochondrial dysfunction Vesicle-mediated transport Hormone therapy 
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
Unknown2'-Fucosyllactose mitigates cognitive deficits in Alzheimer models: targeting amyloid pathology, oxidative stress, and synaptic plasticity.
Not available
S-EPMC12408522 | biostudies-literature
UnknownThe neuronal protein Neurexin directly interacts with the Scribble-Pix complex to stimulate F-actin assembly for synaptic vesicle clustering.
Not available
S-EPMC5582829 | biostudies-literature
UnknownOverexpression of synaptic vesicle protein Rab GTPase 3C promotes vesicular exocytosis and drug resistance in colorectal cancer cells.
Not available
S-EPMC9980308 | biostudies-literature
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