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Proteomicshuman synovium micro-regional proteomics analysis
To analyze synovium proteome heterogeneity in different position via LCM separation.
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD059879 | Pride
Synovium Dia 
TranscriptomicsSingle cell RNA-sequencing of the human synovium in inflammatory arthritis
The study presents: - an optimized synovium dissociation protocol for single cell RNA-sequencing studies of the human synovium. The protocol enables the isolation of high yield of viable synovial cells from prospectively collected fresh synovial biopsies from patients with inflammatory arthritis wi...
ORGANISM(S): Homo sapiens 
2024-04-21 | E-MTAB-11791 | biostudies-arrayexpress
ProteomicsHuman synovium regional proteomics analysis
To analyze regional expression differences of proteins in human synovium
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD059875 | Pride
Synovium Regional proteomics Lcm 
TranscriptomicsRheumatoid arthritis and rheumatoid synovium
Rheumatoid arthritis (RA) is a heterogeneous disease. We used cDNA microarray technology to subclassify RA patients and disclose disease pathways in rheumatoid synovium. Hierarchical clustering of gene expression data identified two main groups of tissues (RA-I and RA-II). A total of 121 genes were ...
ORGANISM(S): Homo sapiens 
2005-12-14 | E-GEOD-3824 | biostudies-arrayexpress
TranscriptomicsHuman transcripts up-regulated in the human mesenchymal stem cells migrated within the synovium
After the injection of human synovial mesenchymal stem cells into the rat (Lewis strain) knee joint, synovium was investigated using species specific microarray analyses of human and rat transcripts to investigate the gene expression change after injection. Human synovial mesenchymal stem cells were...
ORGANISM(S): Homo sapiens 
2014-09-22 | E-GEOD-61617 | biostudies-arrayexpress
TranscriptomicsTranscriptional Profiling of Synovium in a Porcine Model of Early Post-traumatic Osteoarthritis
36 Yucatan minipigs underwent anterior cruciate ligament (ACL) transection and were randomly assigned in equal numbers to no further treatment, reconstruction or ligament repair. Peri-meniscal synovium was harvested at 1 and 4 weeks post-operatively and histology and RNA-sequencing performed. The ge...
ORGANISM(S): Sus scrofa 
2018-04-21 | E-MTAB-6664 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Rheumatoid arthritis patients to disclose disease pathways in rheumatoid synovium
Rheumatoid arthritis (RA) is a heterogeneous disease. We used cDNA microarray technology to subclassify RA patients and disclose disease pathways in rheumatoid synovium. Hierarchical clustering of gene expression data identified two main groups of tissues (RA-I and RA-II). A total of 121 genes were ...
ORGANISM(S): Homo sapiens 
2005-10-11 | E-SMDB-1874 | biostudies-arrayexpress
TranscriptomicsExpression data from synovium, bone marrow and nucleus pulposus
Synovial and bone marrow mesenchymal stem cells after intradiscally injection show regenerative effects of nucleus pulposus. Microarray analyses of rats were performed to investigate the closeness of the gene profiles between the nucleus pulposus cells and the synovial or bone marrow mesenchymal ste...
ORGANISM(S): Rattus norvegicus 
2010-10-11 | E-GEOD-24612 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse knee joint synovium from different grades of inflammation in mouse collagen induced arthritis (CIA)
Knee joint synovium was used for gene expression analysis of mouse collagen induced arthritis (CIA). Synovium was prepared at day 30 after initial sensitization from: healthy controls, CIA animals with no, with mild, with moderate, or with severe joint inflammation. Each sample group is represente...
ORGANISM(S): Mus musculus 
2009-09-15 | E-GEOD-13071 | biostudies-arrayexpress
TranscriptomicsUtility of Baseline Transcriptomic Analysis of Rheumatoid Arthritis Synovium as an Indicator for Long-term Clinical Outcomes
Intent of this experiment is to define the baseline transcriptome of the synovium obtained from rheumatoid arthritis patients prior to initiation of DMARD (Disease-modifying antirheumatic drug) therapy and compare it with the synovial transcriptome of rheumatoid arthritis patients with an establishe...
ORGANISM(S): Homo sapiens 
2022-06-01 | E-MTAB-11274 | biostudies-arrayexpress
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