Sort   by:  
 Page size 
ProteomicsInteraction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells
The endothelium stores the hemostatic protein Von Willebrand factor (VWF) in endothelial storage organelles called Weibel-Palade bodies (WPBs). During maturation, WPBs recruit a complex of Rab GTPases and effectors that associate with components of the SNARE machinery that control WPB exocytosis. Re...
ORGANISM(S): Homo sapiens (Human) 
2023-01-06 | PXD012809 | Pride
Weibel-palade body  snare protein  syntaxin  protein-protein interactions 
TranscriptomicsTranscription profiling of wild type and mutant Arabidopsis plants innoculated with the host powdery mildew Erysiphe cichoracearum or the non-host barley powdery mildew Blumeria graminis f. sp. hordei
Attack by the host powdery mildew Erysiphe cichoracearum usually results in successful penetration and rapid proliferation of the fungus on Arabidopsis. By contrast, the nonhost barley powdery mildew Blumeria graminis f. sp. hordei (Bgh) typically fails to penetrate Arabidopsis epidermal cells. In b...
ORGANISM(S): Arabidopsis thaliana 
2007-05-11 | E-SMDB-4008 | biostudies-arrayexpress
ProteomicsSyntaxin-3 is a Weibel-Palade body localized SNARE protein that regulates Von Willebrand factor secretion from endothelial cells
Endothelial cells store von Willebrand factor (VWF) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab-effectors and SNARE proteins. We have previously identified STXBP1 as the link between the Rab27A-Slp4-a ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD006176 | Pride
Endothelial cells Proteomics Weibel-palade body Snare machinery Syntaxin-3 Von willebrand factor 
UnknownSyntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion.
Not available
S-EPMC3448260 | biostudies-literature
GenomicsSyntaxin-6 mediated autophagy confers lenvatinib resistance in hepatocellular carcinoma
Syntaxin-6 mediated autophagy confers lenvatinib resistance in hepatocellular carcinoma
PRJNA1204913 | ENA
UnknownDifferential palmitoylation of the endosomal SNAREs syntaxin 7 and syntaxin 8.
Not available
S-EPMC2639088 | biostudies-literature
ProteomicsSyntaxin 4 (STX4) protects islet -cells from cytokine-induced senescence
Syntaxin 4 (STX4) is a plasma membrane SNARE protein known to facilitate insulin granule exocytosis in pancreatic β-cells. Recent studies have uncovered that STX4 also exerts protective effects against inflammatory and metabolic stress by stabilizing mitochondrial function and suppressing NF-κB acti...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-25 | PXD069706 | Pride
Sasp Inflammation Stx4 Type 1 diabetes Beta cell senescence 
UnknownOpen syntaxin docks synaptic vesicles.
Not available
S-EPMC1914072 | biostudies-literature
UnknownHomology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis.
Not available
S-EPMC2652326 | biostudies-literature
GenomicsAging Induced Syntaxin 4 Deficiency Mediates Brown Adipose Tissue Pyroptosis and Thermogenic Dysfunction­­­
Aging Induced Syntaxin 4 Deficiency Mediates Brown Adipose Tissue Pyroptosis and Thermogenic Dysfunction­­­
PRJNA956945 | ENA
Sort   by:  
 Page size