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TranscriptomicsTranscription profiling by array of cancer associated fibroblasts from pancreatic ductal adenocarcinoma in comparison to normal dermal fibroblasts
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor type with extremely high mortality (up to 92%) during 5 years after diagnosis. Here, cancer associated fibroblasts (CAF) from PDAC were compared to CAF from melanoma metastases (MELF) and to normal dermal fibroblasts (DF). The analysis w...
ORGANISM(S): Homo sapiens 
2021-11-01 | E-MTAB-8764 | biostudies-arrayexpress
TranscriptomicsFibroblasts prepared from stroma of basal cell carcinoma in comparison to normal dermal fibroblasts
Adult tissue stem cells are known to participate in cancer formation. Indeed, cells exhibiting markers of embryonic stem cells such as Oct-4 and Nanog were detected in some malignant tumors. In this study we demonstrated that stromal cells prepared from the basal cell carcinoma are able to induce ex...
ORGANISM(S): Homo sapiens 
2011-11-02 | E-MTAB-272 | biostudies-arrayexpress
UnknownDesmoplastic Crosstalk in Pancreatic Ductal Adenocarcinoma Is Reflected by Different Responses of Panc-1, MIAPaCa-2, PaTu-8902, and CAPAN-2 Cell Lines to Cancer-associated/Normal Fibroblasts.
Not available
S-EPMC8126325 | biostudies-literature
TranscriptomicsTranscriptional profiling by array of human head and neck squamous cell carcinoma to study the correlation between galectin-1 upregulation and the presence of SMA positive cancer-associated fibroblasts
In this study, we set the presence of smooth muscle actin (SMA)-positive cancer-associated fibroblasts (CAFs) in relation to galectin-1 and its in vivo competitor (galectin-3). In squamous cell carcinomas of head and neck, upregulation of galectin-1 presence is highly significantly correlated to pre...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MTAB-850 | biostudies-arrayexpress
UnknownUnravelling heterogeneous effects of cancer‑associated fibroblasts on poor prognosis markers in breast cancer EM‑G3 cell line: In vitro‑targeted treatment (anti‑IL-6, anti‑VEGF-A, anti‑MFGE8) based on transcriptomic profiling.
Not available
S-EPMC10688412 | biostudies-literature
UnknownThe HOX code of human adult fibroblasts reflects their ectomesenchymal or mesodermal origin.
Not available
S-EPMC11893657 | biostudies-literature
TranscriptomicsTranscriptome profiling by array of normal fibroblasts and cancer associated fibroblasts (CAF) isolated from breast cancer skin metastasis, cutaneous basal cell carcinoma and squamous cell carcinoma arising from oral cavity mucous membrane
We focus on cancer-associated fibroblasts (CAFs) as an active component of the tumor microenvironment. The transcriptome profiling and analysis of CAFs isolated from breast cancer skin metastasis, cutaneous basal cell carcinoma and squamous cell carcinoma arising from oral cavity mucous membrane unr...
ORGANISM(S): Homo sapiens 
2023-10-02 | E-MTAB-12994 | biostudies-arrayexpress
TranscriptomicsActivation of normal dermal fibroblasts by normal and cancer epithelial cells: clinical samples.
We model processes of wound healing and tumor growth, by studying the effects of normal and cancer epithelial cells on normal fibroblasts and their reciprocal effect on normal keratinocytes in vitro. We find strong parallels between the two processes and compare our observations with transcriptional...
ORGANISM(S): Homo sapiens 
2013-11-02 | E-MTAB-1065 | biostudies-arrayexpress
TranscriptomicsActivation of normal dermal fibroblasts by normal and cancer epithelial cells. Tissue cultures.
We model processes of wound healing and tumor growth, by studying the effects of normal and cancer epithelial cells on normal fibroblasts and their reciprocal effect on normal keratinocytes in vitro. We find strong parallels between the two processes and compare our observations with transcriptional...
ORGANISM(S): Homo sapiens 
2013-11-02 | E-MTAB-1064 | biostudies-arrayexpress
UnknownEarly vs Late Anticoagulation in Minor, Moderate, and Major Ischemic Stroke With Atrial Fibrillation: Post Hoc Analysis of the ELAN Randomized Clinical Trial.
Not available
S-EPMC11134281 | biostudies-literature
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